# annotation

uniprotID: P49910
geneSymbol: ZNF165
length: 485
go: ENSG00000197279;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}.
name:
Zinc finger protein 165 (Cancer/testis antigen 53) (CT53) (LD65) (Zinc finger and SCAN domain-containing protein 7)

sequence:


uniprotID: Q49AA0
geneSymbol: ZFP69
reactome: R-HSA-212436;
name: Zinc finger protein 69 homolog (Zinc finger protein 642)
length: 526
go: ENSG00000187815;
snps: rs34752670
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:A2A761}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; lipid metabolic process [GO:0006629]; regulation of lipid metabolic process [GO:0019216]


uniprotID: Q6U7Q0
geneSymbol: ZNF322
length: 402
go: ENSG00000181315;
name:
Zinc finger protein 322 (Zinc finger protein 322A) (Zinc finger protein 388) (Zinc finger protein 489)

sequence:

opentargets:
centrosome [GO:0005813]; cytosol [GO:0005829]; nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer binding [GO:0035326]; metal ion binding [GO:0046872]; positive regulation of stem cell population maintenance [GO:1902459]

location:
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15555580}. Nucleus {ECO:0000269|PubMed:15555580}. Note=Mainly found in the nucleus. {ECO:0000269|PubMed:15555580}.


uniprotID: Q8NCP5
geneSymbol: ZBTB44
length: 570
go: ENSG00000196323;
snps: rs17857365
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
name:
Zinc finger and BTB domain-containing protein 44 (BTB/POZ domain-containing protein 15) (Zinc finger protein 851)

sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=4;  Name=1; IsoId=Q8NCP5-1; Sequence=Displayed; Name=2; IsoId=Q8NCP5-2; Sequence=VSP_022834; Note=No experimental confirmation available.; Name=3; IsoId=Q8NCP5-3; Sequence=VSP_022836, VSP_022837; Name=4; IsoId=Q8NCP5-4; Sequence=VSP_022835; Note=No experimental confirmation available.; 


uniprotID: Q2M3W8
geneSymbol: ZNF181
name: Zinc finger protein 181 (HHZ181)
length: 571
go: ENSG00000197841;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q2M3W8-1; Sequence=Displayed; Name=2; IsoId=Q2M3W8-2; Sequence=VSP_017824; Note=No experimental confirmation available.; Name=3; IsoId=Q2M3W8-3; Sequence=VSP_043416; Note=No experimental confirmation available.; 


uniprotID: Q16600
geneSymbol: ZNF239
name: Zinc finger protein 239 (Zinc finger protein HOK-2) (Zinc finger protein MOK-2)
length: 458
go: ENSG00000196793;
snps: rs2230660 rs2230661 rs1128865
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001078]; RNA binding [GO:0003723]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]


uniprotID: P17035
geneSymbol: ZNF28
reactome: R-HSA-212436;
name: Zinc finger protein 28 (Zinc finger protein KOX24)
length: 718
go: ENSG00000198538;
snps: rs13382164 rs10417163 rs8107444
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=P17035-1; Sequence=Displayed; Name=2; IsoId=P17035-2; Sequence=VSP_029007; 


uniprotID: Q9BSG1
geneSymbol: ZNF2
reactome: R-HSA-212436;
name: Zinc finger protein 2 (Zinc finger protein 2.2) (Zinc finger protein 661)
length: 426
go: ENSG00000275111;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; zinc ion binding [GO:0008270]; regulation of transcription, DNA-templated [GO:0006355]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=4;  Name=1; IsoId=Q9BSG1-1; Sequence=Displayed; Name=2; IsoId=Q9BSG1-2; Sequence=VSP_047659; Name=3; IsoId=Q9BSG1-3; Sequence=VSP_047658; Note=No experimental confirmation available.; Name=4; IsoId=Q9BSG1-4; Sequence=VSP_054369; Note=No experimental confirmation available.; 


uniprotID: Q08AN1
geneSymbol: ZNF616
reactome: R-HSA-212436;
name: Zinc finger protein 616
length: 781
go: ENSG00000204611;
snps: rs35582075 rs3764537
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q9BY31
geneSymbol: ZNF717
reactome: R-HSA-212436;
name: Zinc finger protein 717 (Krueppel-like factor X17)
length: 904
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: O75123
geneSymbol: ZNF623
name: Zinc finger protein 623
length: 536
snps: rs4874084
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=O75123-1; Sequence=Displayed; Name=2; IsoId=O75123-2; Sequence=VSP_053501; Note=No experimental confirmation available.; 


uniprotID: P10073
geneSymbol: ZSCAN22
length: 491
go: ENSG00000182318;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}.
name:
Zinc finger and SCAN domain-containing protein 22 (Krueppel-related zinc finger protein 2) (Protein HKR2) (Zinc finger protein 50)

sequence:


uniprotID: Q8IXZ2
geneSymbol: ZC3H3
name: Zinc finger CCCH domain-containing protein 3 (Smad-interacting CPSF-like factor)
length: 948
go: ENSG00000014164;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8CHP0}.
sequence:

opentargets:
mRNA cleavage and polyadenylation specificity factor complex [GO:0005847]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; R-SMAD binding [GO:0070412]; mRNA polyadenylation [GO:0006378]; poly(A)+ mRNA export from nucleus [GO:0016973]; positive regulation of activin receptor signaling pathway [GO:0032927]; regulation of mRNA export from nucleus [GO:0010793]

snps:
rs2242093 rs17857167 rs3750206 rs3750207 rs17853852 rs3750208 rs4873802 rs17853853 rs34674128 rs1318196 rs36008851 rs4874147 rs11548254 rs17855618 rs17857164 rs17857168 

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q8IXZ2-1; Sequence=Displayed; Name=2; IsoId=Q8IXZ2-2; Sequence=VSP_010272, VSP_010273; 


uniprotID: A1YPR0
geneSymbol: ZBTB7C
length: 619
go: ENSG00000184828;
name:
Zinc finger and BTB domain-containing protein 7C (Affected by papillomavirus DNA integration in ME180 cells protein 1) (APM-1) (Zinc finger and BTB domain-containing protein 36) (Zinc finger protein 857C)

sequence:

opentargets:
nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; negative regulation of cell proliferation [GO:0008285]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903025]


uniprotID: Q9HCX3
geneSymbol: ZNF304
reactome: R-HSA-212436;
name: Zinc finger protein 304 (KRAB-containing zinc finger protein)
length: 659
go: ENSG00000131845;
snps: rs862708 rs862709
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; promoter-specific chromatin binding [GO:1990841]; angiogenesis [GO:0001525]; chromatin organization [GO:0006325]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of anoikis [GO:2000811]; negative regulation of chromatin binding [GO:0035562]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of histone H3-K27 trimethylation [GO:1902466]; positive regulation of histone H3-K9 trimethylation [GO:1900114]; positive regulation of methylation-dependent chromatin silencing [GO:0090309]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Ras protein signal transduction [GO:0007265]

location:
SUBCELLULAR LOCATION: Nucleus {ECO:0000305|PubMed:24623306}. Note=Associates with chromatin (PubMed:24623306). {ECO:0000269|PubMed:24623306}.


uniprotID: O94892
geneSymbol: ZNF432
reactome: R-HSA-212436;
name: Zinc finger protein 432
length: 652
go: ENSG00000256087;
snps: rs755035378
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q2M218
geneSymbol: ZNF630
name: Zinc finger protein 630
length: 657
go: ENSG00000221994;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; regulation of transcription, DNA-templated [GO:0006355]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q2M218-1; Sequence=Displayed; Name=2; IsoId=Q2M218-2; Sequence=VSP_046855; Note=No experimental confirmation available.; 


uniprotID: Q8IYP9
geneSymbol: ZDHHC23
length: 409
go: ENSG00000184307;
snps: rs17853401 rs17853402 rs11921691 rs17857054
location: SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
name:
Palmitoyltransferase ZDHHC23 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 23) (DHHC-23) (zDHHC23)

sequence:

opentargets:
endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein localization to plasma membrane [GO:0072659]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612]


uniprotID: O15535
geneSymbol: ZSCAN9
length: 394
go: ENSG00000137185;
snps: rs148219046
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}.
name:
Zinc finger and SCAN domain-containing protein 9 (Cell proliferation-inducing gene 12 protein) (PRD51) (Zinc finger protein 193)

sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=O15535-1; Sequence=Displayed; Name=2; IsoId=O15535-2; Sequence=VSP_044798; Note=No experimental confirmation available.; 


uniprotID: Q96K62
geneSymbol: ZBTB45
name: Zinc finger and BTB domain-containing protein 45 (Zinc finger protein 499)
length: 511
go: ENSG00000119574;
snps: rs35430780
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; nervous system development [GO:0007399]


uniprotID: P17098
geneSymbol: ZNF8
name: Zinc finger protein 8 (Zinc finger protein HF.18)
length: 575
go: ENSG00000278129;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; zinc ion binding [GO:0008270]; BMP signaling pathway [GO:0030509]; negative regulation of transcription by RNA polymerase II [GO:0000122]


uniprotID: Q8IZC7
geneSymbol: ZNF101
reactome: R-HSA-212436;
name: Zinc finger protein 101 (Zinc finger protein HZF12)
length: 436
go: ENSG00000181896;
snps: rs4808209
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q8IZC7-1; Sequence=Displayed; Name=2; IsoId=Q8IZC7-2; Sequence=VSP_055937; Note=No experimental confirmation available.; 


uniprotID: Q9H8N7
geneSymbol: ZNF395
length: 513
go: ENSG00000186918;
location: SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=May shuttle between nucleus and cytoplasm.
name:
Zinc finger protein 395 (HD-regulating factor 2) (HDRF-2) (Huntington disease gene regulatory region-binding protein 2) (HD gene regulatory region-binding protein 2) (HDBP-2) (Papillomavirus regulatory factor 1) (PRF-1) (Papillomavirus-binding factor)

sequence:

opentargets:
cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; enhancer sequence-specific DNA binding [GO:0001158]; metal ion binding [GO:0046872]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; regulation of transcription, DNA-templated [GO:0006355]


uniprotID: Q9H7S9
geneSymbol: ZNF703
reactome: R-HSA-212436;
name: Zinc finger protein 703 (Zinc finger elbow-related proline domain protein 1)
length: 590
go: ENSG00000183779;
sequence:

opentargets:
cytoplasm [GO:0005737]; nuclear matrix [GO:0016363]; nucleus [GO:0005634]; protein-containing complex [GO:0032991]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; repressing transcription factor binding [GO:0070491]; adherens junction assembly [GO:0034333]; cellular response to estradiol stimulus [GO:0071392]; mammary gland epithelial cell differentiation [GO:0060644]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of cell migration [GO:0030335]; positive regulation of cell proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of mammary gland epithelial cell proliferation [GO:0033601]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of cell cycle [GO:0051726]; regulation of transcription, DNA-templated [GO:0006355]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]

location:
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:21328542, ECO:0000269|PubMed:21337521}. Cytoplasm {ECO:0000250}.


uniprotID: P17029
geneSymbol: ZKSCAN1
reactome: R-HSA-212436;
length: 563
go: ENSG00000106261;
snps: rs17851996
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}.
name:
Zinc finger protein with KRAB and SCAN domains 1 (Zinc finger protein 139) (Zinc finger protein 36) (Zinc finger protein KOX18)

sequence:


uniprotID: Q8TF45
geneSymbol: ZNF418
reactome: R-HSA-212436;
name: Zinc finger protein 418
length: 676
go: ENSG00000196724;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]


uniprotID: Q2VY69
geneSymbol: ZNF284
name: Zinc finger protein 284
length: 593
go: ENSG00000186026;
snps: rs8113249 rs8113249
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q9H6R6
geneSymbol: ZDHHC6
length: 413
go: ENSG00000023041;
snps: rs34350728
name:
Palmitoyltransferase ZDHHC6 (EC 2.3.1.225) (Transmembrane protein H4) (Zinc finger DHHC domain-containing protein 6) (DHHC-6) (Zinc finger protein 376)

sequence:

opentargets:
endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9H6R6-1; Sequence=Displayed; Name=2; IsoId=Q9H6R6-2; Sequence=VSP_006938; Note=No experimental confirmation available.; 

location:
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:21926431, ECO:0000269|PubMed:22314232, ECO:0000269|PubMed:28826475}; Multi-pass membrane protein {ECO:0000255}. Note=When not palmitoylated, accumulates to dot-like structures in the endoplasmic reticulum (PubMed:28826475). {ECO:0000269|PubMed:28826475}.


uniprotID: Q6PML9
geneSymbol: SLC30A9
pdb: 2ENK;
length: 568
go: ENSG00000014824;
snps: rs1047626 rs2581423 rs1801962
name:
Zinc transporter 9 (ZnT-9) (Human embryonic lung protein) (HuEL) (Solute carrier family 30 member 9)

sequence:

opentargets:
cytoplasmic vesicle [GO:0031410]; cytoskeleton [GO:0005856]; endoplasmic reticulum [GO:0005783]; integral component of membrane [GO:0016021]; nucleus [GO:0005634]; cation transmembrane transporter activity [GO:0008324]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nuclear receptor binding [GO:0016922]; nuclear receptor transcription coactivator activity [GO:0030374]; cellular zinc ion homeostasis [GO:0006882]; nucleotide-excision repair [GO:0006289]; positive regulation of transcription by RNA polymerase II [GO:0045944]; zinc ion transport [GO:0006829]

location:
SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Nucleus {ECO:0000269|PubMed:10409434}. Cytoplasm {ECO:0000269|PubMed:10409434}. Cytoplasmic vesicle {ECO:0000269|PubMed:28334855}. Endoplasmic reticulum {ECO:0000269|PubMed:28334855}. Note=Mainly in the cytoplasm (PubMed:10409434). Partial co-localization with endoplasmic reticulum (PubMed:28334855). {ECO:0000269|PubMed:10409434, ECO:0000269|PubMed:28334855}.


uniprotID: Q15929
geneSymbol: ZNF56
name: Putative zinc finger protein 56 (Putative zinc finger protein 742)
length: 161
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
sequence:
MGPLQFRDVAIEFSLEEWHCLDTAQWNLYRDVMLENYRHLVFLVCGKAFNSSSNLTTHKKIHTGEKPYRCEECGKAFKRSSHLTVHKIVHTGEKSYKCEECGKAFKHPSHVTAHKKIHTGGKPYKCEECGKDFKYTSTLIAHKRIHTGEKPYKCEECGKDF

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; regulation of transcription, DNA-templated [GO:0006355]


uniprotID: Q8NDX6
geneSymbol: ZNF740
reactome: R-HSA-212436;
name: Zinc finger protein 740 (OriLyt TD-element-binding protein 7)
length: 193
go: ENSG00000139651;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:
MAQASLLACEGLAGVSLVPTAASKKMMLSQIASKQAENGERAGSPDVLRCSSQGHRKDSDKSRSRKDDDSLSEASHSKKTVKKVVVVEQNGSFQVKIPKNFVCEHCFGAFRSSYHLKRHILIHTGEKPFECDICDMRFIQKYHLERHKRVHSGEKPYQCERCHQCFSRTDRLLRHKRMCQGCQSKTSDGQFSL

opentargets:
nucleoplasm [GO:0005654]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]; positive regulation of transcription by RNA polymerase II [GO:0045944]


uniprotID: Q96EF9
geneSymbol: ZHX1-C8orf76
name: Zinc fingers and homeoboxes protein 1, isoform 2 (ZHX1-C8orf76 readthrough transcript protein)
length: 292
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=2; Synonyms=ZHX1-C8orf76; IsoId=Q96EF9-1; Sequence=Displayed; Note=Based on a readthrough transcript which may produce a ZHX1-C8orf76 fusion protein. No experimental confirmation available.; Name=1; IsoId=Q9UKY1-1; Sequence=External; Name=3; IsoId=Q96K31-1; Sequence=External; 


uniprotID: Q14929
geneSymbol: ZNF169
reactome: R-HSA-212436;
name: Zinc finger protein 169
length: 603
go: ENSG00000175787;
snps: rs1536690 rs35177967 rs34433105 rs12236219 rs12350212
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q86UP3
geneSymbol: ZFHX4
name: Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4)
length: 3567
go: ENSG00000091656;
snps: rs16919452 rs16939380
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription regulatory region DNA binding [GO:0044212]; zinc ion binding [GO:0008270]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription, DNA-templated [GO:0045893]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=5;  Name=1; IsoId=Q86UP3-1; Sequence=Displayed; Name=2; IsoId=Q86UP3-2; Sequence=VSP_023298, VSP_023301, VSP_023302, VSP_023303, VSP_023304; Note=No experimental confirmation available.; Name=3; IsoId=Q86UP3-3; Sequence=VSP_023299, VSP_023300; Note=No experimental confirmation available.; Name=4; IsoId=Q86UP3-4; Sequence=VSP_023304; Name=5; IsoId=Q86UP3-5; Sequence=VSP_023298, VSP_023301, VSP_023302, VSP_023304; 


uniprotID: Q9UJ78
geneSymbol: ZMYM5
pdb: 2DAS;
name: Zinc finger MYM-type protein 5 (Zinc finger protein 198-like 1) (Zinc finger protein 237)
length: 669
go: ENSG00000132950;
snps: rs9579718 rs9579717 rs41292167
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleoplasm [GO:0005654]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; zinc ion binding [GO:0008270]; cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604]; regulation of transcription by RNA polymerase II [GO:0006357]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=5;  Name=4; IsoId=Q9UJ78-4; Sequence=Displayed; Note=No experimental confirmation available.; Name=1; IsoId=Q9UJ78-1; Sequence=VSP_034646, VSP_034647; Name=2; IsoId=Q9UJ78-2; Sequence=VSP_011443, VSP_011444; Name=3; IsoId=Q9UJ78-3; Sequence=VSP_011442, VSP_011445; Name=5; IsoId=Q9UJ78-5; Sequence=VSP_034645; Note=No experimental confirmation available.; 


uniprotID: Q99726
geneSymbol: SLC30A3
reactome: R-HSA-435368;
name: Zinc transporter 3 (ZnT-3) (Solute carrier family 30 member 3)
length: 388
go: ENSG00000115194;
snps: rs146572471
sequence:

opentargets:
cell junction [GO:0030054]; cytoplasm [GO:0005737]; endosome [GO:0005768]; glutamatergic synapse [GO:0098978]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; integral component of plasma membrane [GO:0005887]; integral component of synaptic vesicle membrane [GO:0030285]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; synaptic vesicle [GO:0008021]; zinc ion transmembrane transporter activity [GO:0005385]; zinc-transporting ATPase activity [GO:0015633]; positive regulation of transport [GO:0051050]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; zinc ion import into synaptic vesicle [GO:0099180]; zinc ion transmembrane transport [GO:0071577]

location:
SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:P97441}; Multi-pass membrane protein {ECO:0000255}. Cell junction, synapse, synaptosome {ECO:0000250|UniProtKB:P97441}. Late endosome membrane {ECO:0000269|PubMed:17349999}; Multi-pass membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000269|PubMed:17349999}; Multi-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000269|PubMed:26647834}.


uniprotID: O95201
geneSymbol: ZNF205
reactome: R-HSA-212436;
name: Zinc finger protein 205 (Zinc finger protein 210)
length: 554
go: ENSG00000122386;
snps: rs909410 rs12445220
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
mitochondrion [GO:0005739]; nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; zinc ion binding [GO:0008270]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of hydrogen peroxide biosynthetic process [GO:0010729]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription, DNA-templated [GO:0006355]


uniprotID: Q68DI1
geneSymbol: ZNF776
reactome: R-HSA-212436;
name: Zinc finger protein 776
length: 518
go: ENSG00000152443;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: A6NGD5
geneSymbol: ZSCAN5C
length: 496
go: ENSG00000204532;
snps: rs10419548 rs4801690 rs12979551 rs1865102
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}.
name:
Putative zinc finger and SCAN domain-containing protein 5C (Zinc finger and SCAN domain-containing protein 5C pseudogene)

sequence:

opentargets:
nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]


uniprotID: Q8N7M2
geneSymbol: ZNF283
name: Zinc finger protein 283 (Zinc finger protein HZF19)
length: 679
go: ENSG00000167637;
snps: rs2195980 rs1061768 rs2356437 rs1061769 rs10417624
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: P0CG24
geneSymbol: ZNF883
name: Zinc finger protein 883
length: 379
opentargets: nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
sequence:


uniprotID: Q96PM9
geneSymbol: ZNF385A
reactome: R-HSA-6804114;R-HSA-6804116;R-HSA-6804759;R-HSA-69895;
name: Zinc finger protein 385A (Hematopoietic zinc finger protein) (Retinal zinc finger protein)
length: 386
go: ENSG00000161642;
sequence:

opentargets:
cytoplasm [GO:0005737]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; mRNA 3'-UTR binding [GO:0003730]; p53 binding [GO:0002039]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; hemostasis [GO:0007599]; learning or memory [GO:0007611]; locomotory behavior [GO:0007626]; megakaryocyte development [GO:0035855]; mRNA localization resulting in posttranscriptional regulation of gene expression [GO:0010609]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; platelet alpha granule organization [GO:0070889]; platelet formation [GO:0030220]; positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:1902164]; positive regulation of fat cell differentiation [GO:0045600]; regulation of cytoplasmic translation [GO:2000765]; regulation of signal transduction by p53 class mediator [GO:1901796]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=4;  Name=4; IsoId=Q96PM9-4; Sequence=Displayed; Name=1; IsoId=Q96PM9-1; Sequence=VSP_047448; Name=2; IsoId=Q96PM9-2; Sequence=VSP_047448, VSP_047449; Note=No experimental confirmation available.; Name=3; IsoId=Q96PM9-3; Sequence=VSP_047449; 

location:
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15527981}. Nucleus, nucleolus {ECO:0000269|PubMed:15527981}. Cell projection, dendrite {ECO:0000250}. Note=Detected in dendrites of Purkinje cells and hippocampal neurons. {ECO:0000250}.


uniprotID: P17021
geneSymbol: ZNF17
reactome: R-HSA-212436;
name: Zinc finger protein 17 (Zinc finger protein HPF3) (Zinc finger protein KOX10)
length: 662
snps: rs2014827
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=P17021-1; Sequence=Displayed; Name=2; IsoId=P17021-2; Sequence=VSP_036651; Name=3; IsoId=P17021-3; Sequence=VSP_036652; 


uniprotID: P17022
geneSymbol: ZNF18
reactome: R-HSA-212436;
length: 549
go: ENSG00000154957;
snps: rs17857095 rs17853545
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}.
name:
Zinc finger protein 18 (Heart development-specific gene 1 protein) (Zinc finger protein 535) (Zinc finger protein KOX11) (Zinc finger protein with KRAB and SCAN domains 6)

sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=P17022-1; Sequence=Displayed; Name=2; IsoId=P17022-2; Sequence=VSP_016947; 


uniprotID: Q8WW36
geneSymbol: ZCCHC13
name: Zinc finger CCHC domain-containing protein 13
length: 166
go: ENSG00000187969;
opentargets: nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]
sequence:
MSSKDFFACGHSGHWARGCPRGGAGGRRGGGHGRGSQCGSTTLSYTCYCCGESGRNAKNCVLLGNICYNCGRSGHIAKDCKDPKRERRQHCYTCGRLGHLARDCDRQKEQKCYSCGKLGHIQKDCAQVKCYRCGEIGHVAINCSKARPGQLLPLRQIPTSSQGMSQ


uniprotID: Q5JVG8
geneSymbol: ZNF506
reactome: R-HSA-212436;
name: Zinc finger protein 506
length: 444
go: ENSG00000081665;
snps: rs16996376
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleolus [GO:0005730]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q5JVG8-1; Sequence=Displayed; Name=2; IsoId=Q5JVG8-2; Sequence=VSP_040653; 


uniprotID: Q9H609
geneSymbol: ZNF576
name: Zinc finger protein 576
length: 170
go: ENSG00000124444;
snps: rs17849705
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:
MEDPNPEENMKQQDSPKERSPQSPGGNICHLGAPKCTRCLITFADSKFQERHMKREHPADFVAQKLQGVLFICFTCARSFPSSKALITHQRSHGPAAKPTLPVATTTAQPTFPCPDCGKTFGQAVSLRRHRQMHEVRAPPGTFACTECGQDFAQEAGLHQHYIRHARGEL


uniprotID: P13682
geneSymbol: ZNF35
name: Zinc finger protein 35 (Zinc finger protein HF.10)
length: 527
go: ENSG00000169981;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
cell [GO:0005623]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; cellular response to retinoic acid [GO:0071300]; regulation of transcription, DNA-templated [GO:0006355]; spermatogenesis [GO:0007283]


uniprotID: Q9NXF8
geneSymbol: ZDHHC7
name: Palmitoyltransferase ZDHHC7 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 7) (DHHC-7)
length: 308
go: ENSG00000153786;
snps: rs13334011
sequence:

opentargets:
endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9NXF8-1; Sequence=Displayed; Name=2; IsoId=Q9NXF8-2; Sequence=VSP_006942; 

location:
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000269|PubMed:22031296}; Multi-pass membrane protein {ECO:0000255}.


uniprotID: Q5JNZ3
geneSymbol: ZNF311
reactome: R-HSA-212436;
name: Zinc finger protein 311 (Zinc finger protein zfp-31)
length: 666
go: ENSG00000197935;
snps: rs9295783 rs6456880
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q5T619
geneSymbol: ZNF648
name: Zinc finger protein 648
length: 568
go: ENSG00000179930;
snps: rs12564283 rs12568050
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q9BS31
geneSymbol: ZNF649
reactome: R-HSA-212436;
name: Zinc finger protein 649
length: 505
go: ENSG00000198093;
snps: rs6509593 rs1433083
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15950191}.
sequence:

opentargets:
extracellular space [GO:0005615]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]


uniprotID: Q9Y2D9
geneSymbol: ZNF652
name: Zinc finger protein 652
length: 606
go: ENSG00000198740;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]


uniprotID: Q96BV0
geneSymbol: ZNF775
reactome: R-HSA-212436;
name: Zinc finger protein 775
length: 537
go: ENSG00000196456;
snps: rs13225910
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q9H8U3
geneSymbol: ZFAND3
pdb: 1X4W;
name: AN1-type zinc finger protein 3 (Testis-expressed protein 27)
length: 227
go: ENSG00000156639;
opentargets: DNA binding [GO:0003677]; zinc ion binding [GO:0008270]
sequence:


uniprotID: Q6NX49
geneSymbol: ZNF544
reactome: R-HSA-212436;
name: Zinc finger protein 544
length: 715
go: ENSG00000198131;
snps: rs6510130 rs260462
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q8IVP9
geneSymbol: ZNF547
reactome: R-HSA-212436;
name: Zinc finger protein 547
length: 402
go: ENSG00000152433;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q8IVP9-1; Sequence=Displayed; Name=2; IsoId=Q8IVP9-2; Sequence=VSP_016347, VSP_016348; Note=No experimental confirmation available.; 


uniprotID: P98168
geneSymbol: ZXDA
name: Zinc finger X-linked protein ZXDA
length: 799
go: ENSG00000198205;
snps: rs139564495 rs1057327
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; C2H2 zinc finger domain binding [GO:0070742]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; positive regulation of transcription, DNA-templated [GO:0045893]


uniprotID: Q5VUA4
geneSymbol: ZNF318
name: Zinc finger protein 318 (Endocrine regulatory protein)
length: 2279
go: ENSG00000171467;
snps: rs34541323 rs141660717 rs9357410 rs10948072 rs3734684 rs36107018 rs1459675
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:9853615}.
sequence:

opentargets:
cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleic acid binding [GO:0003676]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270]; meiotic cell cycle [GO:0051321]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription, DNA-templated [GO:0045893]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q5VUA4-1; Sequence=Displayed; Name=2; IsoId=Q5VUA4-2; Sequence=VSP_016592, VSP_016593; Note=May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.; 


uniprotID: Q9BV97
geneSymbol: ZNF747
reactome: R-HSA-212436;
name: KRAB domain-containing protein ZNF747
length: 191
go: ENSG00000169955;
sequence:
MTDPSLGLTVPMAPPLAPLPPRDPNGAGSEWRKPGAVSFADVAVYFSREEWGCLRPAQRALYRDVMRETYGHLGALGESPTCLPGPCASTGPAAPLGAACGVGGPGAGQAASSQRGVCVLLPQESEAASRRSSPGWRRRPNCGIRLPRIRRWRSVRQKRTQQIPETRKRKDKGKGREPWRSPTLWPPGLLG

opentargets:
intracellular [GO:0005622]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nucleic acid binding [GO:0003676]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9BV97-1; Sequence=Displayed; Name=2; IsoId=Q9BV97-2; Sequence=VSP_026557; 


uniprotID: Q9Y6M5
geneSymbol: SLC30A1
reactome: R-HSA-435368;
name: Zinc transporter 1 (ZnT-1) (Solute carrier family 30 member 1)
length: 507
go: ENSG00000170385;
location: SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
sequence:

opentargets:
cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of postsynaptic density membrane [GO:0099061]; nuclear membrane [GO:0031965]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685]; T-tubule [GO:0030315]; calcium channel inhibitor activity [GO:0019855]; zinc ion transmembrane transporter activity [GO:0005385]; cadmium ion transmembrane transport [GO:0070574]; calcium ion import [GO:0070509]; cellular calcium ion homeostasis [GO:0006874]; cellular zinc ion homeostasis [GO:0006882]; detoxification of cadmium ion [GO:0071585]; in utero embryonic development [GO:0001701]; negative regulation of calcium ion import [GO:0090281]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of zinc ion transmembrane import [GO:0071584]; zinc ion transport [GO:0006829]


uniprotID: Q9C0D7
geneSymbol: ZC3H12C
length: 883
go: ENSG00000149289;
opentargets: endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
name:
Probable ribonuclease ZC3H12C (EC 3.1.-.-) (MCP-induced protein 3) (Zinc finger CCCH domain-containing protein 12C)

sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9C0D7-1; Sequence=Displayed; Name=2; IsoId=Q9C0D7-2; Sequence=VSP_054127; Note=No experimental confirmation available.; 


uniprotID: Q9Y6Q3
geneSymbol: ZFP37
reactome: R-HSA-212436;
name: Zinc finger protein 37 homolog (Zfp-37)
length: 630
go: ENSG00000136866;
snps: rs2282076
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; zinc ion binding [GO:0008270]; regulation of transcription, DNA-templated [GO:0006355]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q9Y6Q3-1; Sequence=Displayed; Name=2; IsoId=Q9Y6Q3-2; Sequence=VSP_037941; Note=No experimental confirmation available.; Name=3; IsoId=Q9Y6Q3-3; Sequence=VSP_055044; Note=No experimental confirmation. Gene prediction based on EST data.; 


uniprotID: Q9H869
geneSymbol: YY1AP1
length: 796
go: ENSG00000163374;
snps: rs35098429 rs7539
name:
YY1-associated protein 1 (Hepatocellular carcinoma susceptibility protein) (Hepatocellular carcinoma-associated protein 2)

sequence:

opentargets:
cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; cell differentiation [GO:0030154]; cell proliferation [GO:0008283]; regulation of cell cycle [GO:0051726]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=9;  Name=1; IsoId=Q9H869-1; Sequence=Displayed; Name=2; IsoId=Q9H869-2; Sequence=VSP_016588, VSP_016589; Name=3; IsoId=Q9H869-3; Sequence=VSP_016587, VSP_016589; Name=4; IsoId=Q9H869-4; Sequence=VSP_016588; Name=5; IsoId=Q9H869-5; Sequence=VSP_016586, VSP_016589; Name=6; Synonyms=HCCA1; IsoId=Q9H869-6; Sequence=VSP_016587; Name=7; IsoId=Q9H869-7; Sequence=VSP_016585; Name=8; IsoId=Q9H869-8; Sequence=VSP_046858; Note=No experimental confirmation available.; Name=9; IsoId=Q9H869-9; Sequence=VSP_046858, VSP_016589; Note=No experimental confirmation available.; 

location:
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:11710830, ECO:0000269|PubMed:12118372}. Nucleus {ECO:0000269|PubMed:14744866, ECO:0000269|PubMed:17541814}. Nucleus, nucleoplasm {ECO:0000269|PubMed:27939641}. Nucleus, nucleolus {ECO:0000269|PubMed:27939641}.


uniprotID: Q96SE7
geneSymbol: ZNF347
reactome: R-HSA-212436;
pdb: 2EMA;2EMP;2EN4;2ENE;2ENF;2EOE;2EOW;2EQ0;2EQ1;2EQ2;2EQ3;2YTI;2YTK;2YTN;2YTR;2YU8;
name: Zinc finger protein 347 (Zinc finger protein 1111)
length: 839
go: ENSG00000197937;
snps: rs34656962 rs2195310
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q96SE7-1; Sequence=Displayed; Name=2; IsoId=Q96SE7-2; Sequence=VSP_046841; Note=No experimental confirmation available.; 


uniprotID: Q15326
geneSymbol: ZMYND11
pdb: 4NS5;5HDA;
length: 602
go: ENSG00000015171;
name:
Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A-binding protein) (Bone morphogenetic protein receptor-associated molecule 1) (Protein BS69)

sequence:

opentargets:
chromosome [GO:0005694]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; double-stranded DNA binding [GO:0003690]; methylated histone binding [GO:0035064]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270]; cell cycle [GO:0007049]; cell proliferation [GO:0008283]; chromatin organization [GO:0006325]; defense response to virus [GO:0051607]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of JNK cascade [GO:0046329]; regulation of transcription elongation from RNA polymerase II promoter [GO:0034243]; viral process [GO:0016032]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=6;  Name=1; IsoId=Q15326-1; Sequence=Displayed; Name=2; IsoId=Q15326-2; Sequence=VSP_044482; Name=3; IsoId=Q15326-3; Sequence=VSP_044483; Name=4; IsoId=Q15326-4; Sequence=VSP_044482, VSP_044483; Name=5; IsoId=Q15326-5; Sequence=VSP_044482, VSP_046246; Note=No experimental confirmation available.; Name=6; IsoId=Q15326-6; Sequence=VSP_047209, VSP_044483; Note=No experimental confirmation available.; 

location:
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16565076, ECO:0000269|PubMed:19766626, ECO:0000269|PubMed:24675531}. Chromosome {ECO:0000269|PubMed:16565076}. Note=Associates with chromatin and mitotic chromosomes. {ECO:0000269|PubMed:16565076}.


uniprotID: Q9UGI0
geneSymbol: ZRANB1
reactome: R-HSA-5689896;
pdb: 3ZRH;5AF6;
length: 708
go: ENSG00000019995;
location: SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Enriched in punctate localization in the cytoplasm.
name:
Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (TRAF-binding domain-containing protein) (hTrabid) (Zinc finger Ran-binding domain-containing protein 1)

sequence:

opentargets:
cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; metal ion binding [GO:0046872]; thiol-dependent ubiquitin-specific protease activity [GO:0004843]; thiol-dependent ubiquitinyl hydrolase activity [GO:0036459]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; positive regulation of Wnt signaling pathway [GO:0030177]; protein deubiquitination [GO:0016579]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K63-linked deubiquitination [GO:0070536]; regulation of cell morphogenesis [GO:0022604]; Wnt signaling pathway [GO:0016055]


uniprotID: O15060
geneSymbol: ZBTB39
name: Zinc finger and BTB domain-containing protein 39
length: 712
go: ENSG00000166860;
snps: rs3741576
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q9UIE0
geneSymbol: ZNF230
reactome: R-HSA-212436;
name: Zinc finger protein 230 (Zinc finger protein FDZF2)
length: 474
go: ENSG00000159882;
snps: rs1060877 rs6413542 rs12753
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: O60304
geneSymbol: ZNF500
reactome: R-HSA-212436;
name: Zinc finger protein 500 (Zinc finger protein with KRAB and SCAN domains 18)
length: 480
go: ENSG00000103199;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}.
sequence:

opentargets:
cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=O60304-1; Sequence=Displayed; Name=2; IsoId=O60304-2; Sequence=VSP_055962; Note=No experimental confirmation available.; 


uniprotID: Q8NB42
geneSymbol: ZNF527
name: Zinc finger protein 527
length: 609
go: ENSG00000189164;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q8NB42-1; Sequence=Displayed; Name=2; IsoId=Q8NB42-2; Sequence=VSP_040341; 


uniprotID: Q9UHR6
geneSymbol: ZNHIT2
pdb: 1X4S;
name: Zinc finger HIT domain-containing protein 2 (Protein FON)
length: 403
go: ENSG00000174276;
opentargets: metal ion binding [GO:0046872]
snps: rs11556920 rs35983251
sequence:


uniprotID: Q8NCA9
geneSymbol: ZNF784
name: Zinc finger protein 784
length: 323
go: ENSG00000179922;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; hematopoietic progenitor cell differentiation [GO:0002244]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]


uniprotID: Q15916
geneSymbol: ZBTB6
length: 424
go: ENSG00000186130;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:7958847}.
name:
Zinc finger and BTB domain-containing protein 6 (Zinc finger protein 482) (Zinc finger protein with interaction domain)

sequence:

opentargets:
mitochondrion [GO:0005739]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]


uniprotID: Q8N393
geneSymbol: ZNF786
reactome: R-HSA-212436;
name: Zinc finger protein 786
length: 782
go: ENSG00000197362;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q8N393-1; Sequence=Displayed; Name=2; IsoId=Q8N393-2; Sequence=VSP_055971; Note=No experimental confirmation available.; 


uniprotID: Q96JC4
geneSymbol: ZNF479
reactome: R-HSA-212436;
name: Zinc finger protein 479 (Zinc finger protein Kr19) (HKr19)
length: 524
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q9Y2Y4
geneSymbol: ZBTB32
reactome: R-HSA-110314;
pdb: 3M5B;
length: 487
go: ENSG00000011590;
snps: rs2227278
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10572087}. Note=Located in nuclear speckles.
name:
Zinc finger and BTB domain-containing protein 32 (FANCC-interacting protein) (Fanconi anemia zinc finger protein) (Testis zinc finger protein) (Zinc finger protein 538)

sequence:

opentargets:
nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; transcription corepressor activity [GO:0003714]; zinc ion binding [GO:0008270]; negative regulation of transcription by RNA polymerase II [GO:0000122]; transcription by RNA polymerase II [GO:0006366]


uniprotID: Q6ZQV5
geneSymbol: ZNF788P
name: Putative KRAB domain-containing protein ZNF788 (Zinc finger family member 788, pseudogene)
sequence: MRNMIPQDNENPPQQGEANQNDSVAFEDVAVNFTPDEWALLDPSQKNLYREVMQETLRNLASIEVLWKRDSLKVKVISMEKF
length: 82
go: ENSG00000214189;
opentargets:
nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nucleic acid binding [GO:0003676]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q6ZQV5-1; Sequence=Displayed; Name=2; IsoId=Q6ZQV5-2; Sequence=VSP_059376; 


uniprotID: Q9H091
geneSymbol: ZMYND15
name: Zinc finger MYND domain-containing protein 15
length: 742
go: ENSG00000141497;
snps: rs35005394
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
sequence:

opentargets:
cytoplasm [GO:0005737]; nucleus [GO:0005634]; histone deacetylase binding [GO:0042826]; metal ion binding [GO:0046872]; negative regulation of transcription, DNA-templated [GO:0045892]; spermatid development [GO:0007286]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q9H091-1; Sequence=Displayed; Name=2; IsoId=Q9H091-2; Sequence=VSP_042144; Name=3; IsoId=Q9H091-3; Sequence=VSP_047208; Note=No experimental confirmation available.; 


uniprotID: Q2TB10
geneSymbol: ZNF800
name: Zinc finger protein 800
length: 664
go: ENSG00000048405;
snps: rs17865569
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q2QGD7
geneSymbol: ZXDC
name: Zinc finger protein ZXDC (ZXD-like zinc finger protein)
length: 858
go: ENSG00000070476;
snps: rs16837497
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; C2H2 zinc finger domain binding [GO:0070742]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; LRR domain binding [GO:0030275]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; positive regulation of transcription, DNA-templated [GO:0045893]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q2QGD7-1; Sequence=Displayed; Name=2; IsoId=Q2QGD7-2; Sequence=VSP_026437, VSP_026438; Name=3; Synonyms=ZXDC2; IsoId=Q2QGD7-3; Sequence=VSP_047464, VSP_026437, VSP_026438; Note=Doesn't interact with CIITA. Represses MHC class II transcription possibly via dominant-negative association with isoform 1.; 


uniprotID: A6NK53
geneSymbol: ZNF233
reactome: R-HSA-212436;
name: Zinc finger protein 233
length: 670
go: ENSG00000159915;
snps: rs16978899 rs1233428
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q14588
geneSymbol: ZNF234
reactome: R-HSA-212436;
name: Zinc finger protein 234 (Zinc finger protein 269) (Zinc finger protein HZF4)
length: 700
go: ENSG00000263002;
snps: rs2293587 rs11668974
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q96CX3
geneSymbol: ZNF501
name: Zinc finger protein 501 (Zinc finger protein 52)
length: 271
go: ENSG00000186446;
snps: rs4682752 rs58211979
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleoplasm [GO:0005654]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q96CX3-1; Sequence=Displayed; Name=2; IsoId=Q96CX3-2; Sequence=VSP_010173; Note=May be due to exon skipping.; 


uniprotID: Q8N8Z8
geneSymbol: ZNF441
reactome: R-HSA-212436;
name: Zinc finger protein 441
length: 693
go: ENSG00000197044;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q8N8Z8-1; Sequence=Displayed; Name=2; IsoId=Q8N8Z8-2; Sequence=VSP_039877; 


uniprotID: Q8TF68
geneSymbol: ZNF384
length: 577
go: ENSG00000126746;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
name:
Zinc finger protein 384 (CAG repeat protein 1) (CAS-interacting zinc finger protein) (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (Trinucleotide repeat-containing gene 1 protein)

sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Comment=Additional isoforms seem to exist.; Name=1; IsoId=Q8TF68-1; Sequence=Displayed; Name=2; IsoId=Q8TF68-2; Sequence=VSP_006920; Name=3; IsoId=Q8TF68-3; Sequence=VSP_040314, VSP_040315; Note=No experimental confirmation available.; 


uniprotID: Q9UL40
geneSymbol: ZNF346
pdb: 2MKD;2MKN;
name: Zinc finger protein 346 (Just another zinc finger protein)
length: 294
go: ENSG00000113761;
sequence:

opentargets:
cytoplasm [GO:0005737]; nucleolus [GO:0005730]; nucleus [GO:0005634]; double-stranded RNA binding [GO:0003725]; enzyme binding [GO:0019899]; miRNA binding [GO:0035198]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; positive regulation of apoptotic process [GO:0043065]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q9UL40-1; Sequence=Displayed; Name=2; IsoId=Q9UL40-2; Sequence=VSP_015971; Note=No experimental confirmation available.; Name=3; IsoId=Q9UL40-3; Sequence=VSP_055098; Note=No experimental confirmation available.; 

location:
SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:15254228}. Cytoplasm {ECO:0000269|PubMed:15254228}. Note=Nuclear at steady state, primarily in the nucleolus. Shuttles between the nucleus and cytoplasm when associated with XPO5.


uniprotID: Q8WV37
geneSymbol: ZNF480
reactome: R-HSA-212436;
name: Zinc finger protein 480
length: 535
go: ENSG00000198464;
snps: rs13343641
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15219843}.
sequence:

opentargets:
cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q8WV37-1; Sequence=Displayed; Name=2; IsoId=Q8WV37-2; Sequence=VSP_016214; Note=No experimental confirmation available.; Name=3; IsoId=Q8WV37-3; Sequence=VSP_016215; Note=No experimental confirmation available.; 


uniprotID: Q5FWF4
geneSymbol: ZRANB3
pdb: 5MKW;5MLO;5MLW;5YD8;
length: 1079
go: ENSG00000121988;
snps: rs935615 rs7608121 rs59900519
name:
DNA annealing helicase and endonuclease ZRANB3 (Annealing helicase 2) (AH2) (Zinc finger Ran-binding domain-containing protein 3) [Includes: DNA annealing helicase ZRANB3 (EC 3.6.4.-); Endonuclease ZRANB3 (EC 3.1.-.-)]

sequence:

opentargets:
nuclear replication fork [GO:0043596]; nucleus [GO:0005634]; annealing helicase activity [GO:0036310]; ATP binding [GO:0005524]; endodeoxyribonuclease activity [GO:0004520]; helicase activity [GO:0004386]; K63-linked polyubiquitin modification-dependent protein binding [GO:0070530]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; DNA rewinding [GO:0036292]; negative regulation of DNA recombination [GO:0045910]; replication fork processing [GO:0031297]; replication fork protection [GO:0048478]; response to UV [GO:0009411]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=5;  Name=1; IsoId=Q5FWF4-1; Sequence=Displayed; Name=2; IsoId=Q5FWF4-2; Sequence=VSP_023138, VSP_023139, VSP_023140; Note=No experimental confirmation available.; Name=3; IsoId=Q5FWF4-3; Sequence=VSP_023139; Name=4; IsoId=Q5FWF4-4; Sequence=VSP_044175, VSP_023139; Note=No experimental confirmation available.; Name=5; IsoId=Q5FWF4-5; Sequence=VSP_044176, VSP_044177, VSP_044178; Note=No experimental confirmation available.; 

location:
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:22704558, ECO:0000269|PubMed:22705370, ECO:0000269|PubMed:22759634}. Chromosome {ECO:0000269|PubMed:22704558, ECO:0000269|PubMed:22705370, ECO:0000269|PubMed:22759634}. Note=Following DNA damage, recruited to sites of DNA damage and stalled replication forks by polyubiquitinated PCNA (PubMed:22704558, PubMed:22705370, PubMed:22759634). {ECO:0000269|PubMed:22704558, ECO:0000269|PubMed:22705370, ECO:0000269|PubMed:22759634}.


uniprotID: Q9UC06
geneSymbol: ZNF70
reactome: R-HSA-212436;
name: Zinc finger protein 70 (Zinc finger protein N27C7-1)
length: 446
go: ENSG00000187792;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q8TBZ5
geneSymbol: ZNF502
name: Zinc finger protein 502
length: 544
go: ENSG00000196653;
snps: rs6798400 rs56084453 rs7640654
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; positive regulation by host of viral process [GO:0044794]; positive regulation by host of viral release from host cell [GO:0044791]


uniprotID: P17025
geneSymbol: ZNF182
name: Zinc finger protein 182 (Zinc finger protein 21) (Zinc finger protein KOX14)
length: 639
go: ENSG00000147118;
snps: rs146965366
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=P17025-1; Sequence=Displayed; Name=2; IsoId=P17025-2; Sequence=VSP_043078; Note=No experimental confirmation available.; 


uniprotID: P0CG23
geneSymbol: ZNF853
name: Zinc finger protein 853
length: 659
go: ENSG00000236609;
snps: rs2243563 rs1806552 rs11971880
sequence:

opentargets:
DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]


uniprotID: Q15928
geneSymbol: ZNF141
reactome: R-HSA-212436;
name: Zinc finger protein 141
length: 474
go: ENSG00000131127;
snps: rs2229296 rs955417 rs2018645 rs587776959
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; anatomical structure morphogenesis [GO:0009653]; limb morphogenesis [GO:0035108]; transcription by RNA polymerase II [GO:0006366]


uniprotID: Q96N38
geneSymbol: ZNF714
reactome: R-HSA-212436;
name: Zinc finger protein 714
length: 554
snps: rs2884554 rs10427116 rs10427116
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q96N38-1; Sequence=Displayed; Name=2; IsoId=Q96N38-2; Sequence=VSP_033320, VSP_033321; Name=3; IsoId=Q96N38-3; Sequence=VSP_033319; 


uniprotID: O95218
geneSymbol: ZRANB2
pdb: 1N0Z;2K1P;3G9Y;
length: 330
go: ENSG00000132485;
snps: rs11583800
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:11448987}.
name:
Zinc finger Ran-binding domain-containing protein 2 (Zinc finger protein 265) (Zinc finger, splicing)

sequence:

opentargets:
nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; mRNA processing [GO:0006397]; RNA splicing [GO:0008380]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; Synonyms=ZIS-1; IsoId=O95218-1; Sequence=Displayed; Name=2; Synonyms=ZIS-2; IsoId=O95218-2; Sequence=VSP_024945; 


uniprotID: P15822
geneSymbol: HIVEP1
pdb: 1BBO;3ZNF;4ZNF;
length: 2718
name:
Zinc finger protein 40 (Cirhin interaction protein) (CIRIP) (Gate keeper of apoptosis-activating protein) (GAAP) (Human immunodeficiency virus type I enhancer-binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1)

sequence:

opentargets:
mitochondrion [GO:0005739]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; distal enhancer DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001206]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II distal enhancer sequence-specific DNA binding [GO:0000980]; negative regulation of transcription by RNA polymerase II [GO:0000122]

snps:
rs2228209 rs34221818 rs2228210 rs2228218 rs6900196 rs2228220 rs34258344 rs2228212 rs2228213 rs1126472 rs2228214 rs1042054 

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=P15822-1; Sequence=Displayed; Name=2; Synonyms=Delta 2, GAAP-1; IsoId=P15822-2; Sequence=VSP_037714, VSP_037717; Name=3; Synonyms=GAAP-2; IsoId=P15822-3; Sequence=VSP_037715, VSP_037716; 

location:
SUBCELLULAR LOCATION: Isoform 1: Nucleus.; SUBCELLULAR LOCATION: Isoform 2: Cytoplasm. Nucleus.; SUBCELLULAR LOCATION: Isoform 3: Cytoplasm {ECO:0000269|Ref.2}. Nucleus {ECO:0000269|Ref.2}.


uniprotID: Q9UK13
geneSymbol: ZNF221
reactome: R-HSA-212436;
name: Zinc finger protein 221
length: 617
go: ENSG00000159905;
snps: rs16976937 rs454301 rs439676 rs435590 rs365745 rs366111
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q9ULM2
geneSymbol: ZNF490
reactome: R-HSA-212436;
name: Zinc finger protein 490
length: 529
go: ENSG00000188033;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: O95780
geneSymbol: ZNF682
reactome: R-HSA-212436;
name: Zinc finger protein 682
length: 498
go: ENSG00000197124;
snps: rs7255165 rs2075090 rs17679334
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=O95780-1; Sequence=Displayed; Note=Gene prediction based on EST data.; Name=2; IsoId=O95780-2; Sequence=VSP_018166; Note=No experimental confirmation available.; Name=3; IsoId=O95780-3; Sequence=VSP_044563; Note=No experimental confirmation available.; 


uniprotID: Q32MQ0
geneSymbol: ZNF750
reactome: R-HSA-212436;
name: Zinc finger protein 750
length: 723
go: ENSG00000141579;
snps: rs8074277 rs35653278 rs34687659
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:22364861}.
sequence:

opentargets:
nucleus [GO:0005634]; metal ion binding [GO:0046872]; promoter-specific chromatin binding [GO:1990841]; proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001077]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; cell differentiation [GO:0030154]; epidermis development [GO:0008544]; positive regulation of transcription by RNA polymerase II [GO:0045944]


uniprotID: Q5HYM0
geneSymbol: ZC3H12B
length: 836
go: ENSG00000102053;
opentargets: endonuclease activity [GO:0004519]; metal ion binding [GO:0046872]
name:
Probable ribonuclease ZC3H12B (EC 3.1.-.-) (MCP-induced protein 2) (Zinc finger CCCH domain-containing protein 12B)

sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q5HYM0-1; Sequence=Displayed; Name=2; IsoId=Q5HYM0-2; Sequence=VSP_039896; 


uniprotID: Q9BRI3
geneSymbol: SLC30A2
reactome: R-HSA-435368;
name: Zinc transporter 2 (ZnT-2) (Solute carrier family 30 member 2)
length: 323
go: ENSG00000158014;
snps: rs587776926 rs185398527
sequence:

opentargets:
cytoplasm [GO:0005737]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; lysosomal membrane [GO:0005765]; plasma membrane [GO:0005886]; zinc ion transmembrane transporter activity [GO:0005385]; positive regulation of sequestering of zinc ion [GO:0061090]; regulation of sequestering of zinc ion [GO:0061088]; response to zinc ion [GO:0010043]; zinc ion transmembrane transport [GO:0071577]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9BRI3-1; Sequence=Displayed; Name=2; IsoId=Q9BRI3-2; Sequence=VSP_039754; 

location:
SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000269|PubMed:17897319}; Multi-pass membrane protein {ECO:0000269|PubMed:17897319}.; SUBCELLULAR LOCATION: Isoform 2: Lysosome membrane.


uniprotID: Q8NDZ9
name: Putative uncharacterized protein LOC439951
length: 215
opentargets: extracellular space [GO:0005615]
sequence:


uniprotID: Q8N377
name: Putative uncharacterized protein LOC387726
length: 158
sequence:
MDFRQISPTTCTTPASSSSAAPPTPASSSSAAPPTPASSSSAAPPTPANCSTAAPPTPANCSTAAPPTPASSGSAAPPTPAPDHWWMEAPHHWLPGLLARCGSRQLPSSVGLACFGTAAVPRKPVNWACQGSHGELEASQVGSGKAGPCTPHPSLLGF


uniprotID: Q6ZSR9
name: Uncharacterized protein FLJ45252
length: 355
sequence:


uniprotID: Q9BW85
geneSymbol: YJU2
pdb: 5YZG;
name: YJU2 splicing factor homolog (Coiled-coil domain-containing protein 94)
length: 323
go: ENSG00000105248;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:29301961}.
sequence:

opentargets:
U2-type catalytic step 1 spliceosome [GO:0071006]; mRNA processing [GO:0006397]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; RNA splicing [GO:0008380]


uniprotID: Q14584
geneSymbol: ZNF266
reactome: R-HSA-212436;
name: Zinc finger protein 266 (Zinc finger protein HZF1)
length: 549
go: ENSG00000174652;
snps: rs10515
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: P52739
geneSymbol: ZNF131
reactome: R-HSA-3899300;
name: Zinc finger protein 131
length: 623
go: ENSG00000172262;
sequence:

opentargets:
intermediate filament cytoskeleton [GO:0045111]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001228]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; regulation of transcription, DNA-templated [GO:0006355]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=P52739-1; Sequence=Displayed; Name=2; IsoId=P52739-2; Sequence=VSP_016923; 

location:
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17306895, ECO:0000269|PubMed:22467880, ECO:0000269|PubMed:23404503}. Note=Sumoylation does not affect nuclear localization.


uniprotID: Q6ZMS7
geneSymbol: ZNF783
name: Protein ZNF783
length: 281
go: ENSG00000204946;
snps: rs764239191
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; identical protein binding [GO:0042802]; regulation of transcription, DNA-templated [GO:0006355]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q6ZMS7-1; Sequence=Displayed; Name=2; IsoId=Q6ZMS7-2; Sequence=VSP_055627; Note=No experimental confirmation available. Gene prediction based on EST data.; 


uniprotID: Q86T29
geneSymbol: ZNF605
reactome: R-HSA-212436;
name: Zinc finger protein 605
length: 641
go: ENSG00000196458;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q86T29-1; Sequence=Displayed; Name=2; IsoId=Q86T29-2; Sequence=VSP_043213; 


uniprotID: Q96SK3
geneSymbol: ZNF607
reactome: R-HSA-212436;
name: Zinc finger protein 607
length: 696
go: ENSG00000198182;
snps: rs2909097 rs2385006 rs35735839 rs960689 rs2385006 rs958305 rs17856468
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q96SK3-1; Sequence=Displayed; Name=2; IsoId=Q96SK3-2; Sequence=VSP_037503; Name=3; IsoId=Q96SK3-3; Sequence=VSP_046843; Note=No experimental confirmation available.; 


uniprotID: Q05481
geneSymbol: ZNF91
name: Zinc finger protein 91 (Zinc finger protein HPF7) (Zinc finger protein HTF10)
length: 1191
go: ENSG00000167232;
snps: rs296091 rs449447 rs403356 rs440638 rs12976753 rs296093 rs1821844 rs1821846 rs428549 rs385750
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:23665872}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; zinc ion binding [GO:0008270]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of transposon integration [GO:0070895]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q05481-1; Sequence=Displayed; Name=2; IsoId=Q05481-2; Sequence=VSP_040288; 


uniprotID: Q969W1
geneSymbol: ZDHHC16
length: 377
go: ENSG00000171307;
name:
Palmitoyltransferase ZDHHC16 (EC 2.3.1.225) (Abl-philin 2) (Zinc finger DHHC domain-containing protein 16) (DHHC-16)

sequence:

opentargets:
endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; eye development [GO:0001654]; heart development [GO:0007507]; protein palmitoylation [GO:0018345]; telencephalon development [GO:0021537]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=4;  Name=1; IsoId=Q969W1-1; Sequence=Displayed; Name=2; IsoId=Q969W1-2; Sequence=VSP_008716; Name=3; IsoId=Q969W1-3; Sequence=VSP_016275; Name=4; IsoId=Q969W1-4; Sequence=VSP_016274, VSP_008716; 

location:
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305|PubMed:17123647}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9ESG8}.


uniprotID: O43264
geneSymbol: ZW10
reactome: R-HSA-141444;R-HSA-2467813;R-HSA-2500257;R-HSA-5663220;R-HSA-6811434;R-HSA-68877;
name: Centromere/kinetochore protein zw10 homolog
length: 779
go: ENSG00000086827;
snps: rs2271796
sequence:

opentargets:
condensed chromosome kinetochore [GO:0000777]; cytosol [GO:0005829]; Dsl1/NZR complex [GO:0070939]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; kinetochore [GO:0000776]; kinetochore microtubule [GO:0005828]; membrane [GO:0016020]; nucleus [GO:0005634]; RZZ complex [GO:1990423]; spindle pole [GO:0000922]; centromeric DNA binding [GO:0019237]; cell division [GO:0051301]; ER to Golgi vesicle-mediated transport [GO:0006888]; establishment of mitotic spindle orientation [GO:0000132]; Golgi organization [GO:0007030]; meiotic cell cycle [GO:0051321]; mitotic cell cycle checkpoint [GO:0007093]; mitotic metaphase plate congression [GO:0007080]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint [GO:0007094]; protein localization to kinetochore [GO:0034501]; protein transport [GO:0015031]; protein-containing complex assembly [GO:0065003]; regulation of exit from mitosis [GO:0007096]; retrograde vesicle-mediated transport, Golgi to ER [GO:0006890]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=O43264-1; Sequence=Displayed; Name=2; IsoId=O43264-2; Sequence=VSP_056006; Note=No experimental confirmation available.; 

location:
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:15029241}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:15029241}; Peripheral membrane protein {ECO:0000269|PubMed:15029241}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:11590237, ECO:0000269|PubMed:15485811, ECO:0000269|PubMed:15824131}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:11590237}. Note=Dynamic pattern of localization during the cell cycle. In most cells at interphase, present diffusely in the cytoplasm (PubMed:15029241). In prometaphase, associated with the kinetochore. At metaphase, detected both at the kinetochores and, most prominently, at the spindle, particularly at the spindle poles. In very early anaphase, detected on segregating kinetochores. In late anaphase and telophase, accumulates at the spindle midzone (PubMed:11590237). {ECO:0000269|PubMed:11590237, ECO:0000269|PubMed:15029241}.


uniprotID: Q8N8E2
geneSymbol: ZNF513
name: Zinc finger protein 513
length: 541
go: ENSG00000163795;
snps: rs267607182
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:20797688}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]; regulation of gene expression [GO:0010468]; response to stimulus [GO:0050896]; retina development in camera-type eye [GO:0060041]; visual perception [GO:0007601]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q8N8E2-1; Sequence=Displayed; Name=2; IsoId=Q8N8E2-2; Sequence=VSP_035625; Name=3; IsoId=Q8N8E2-3; Sequence=VSP_035624; Note=No experimental confirmation available.; 


uniprotID: Q6ZNC4
geneSymbol: ZNF704
reactome: R-HSA-212436;
name: Zinc finger protein 704
length: 412
go: ENSG00000164684;
snps: rs3907424
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9ERQ3}.
sequence:

opentargets:
nucleus [GO:0005634]; enhancer sequence-specific DNA binding [GO:0001158]; metal ion binding [GO:0046872]; regulation of transcription by RNA polymerase II [GO:0006357]


uniprotID: Q14592
geneSymbol: ZNF460
reactome: R-HSA-212436;
name: Zinc finger protein 460 (Zinc finger protein 272) (Zinc finger protein HZF8)
length: 562
go: ENSG00000197714;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q14592-1; Sequence=Displayed; Name=2; IsoId=Q14592-2; Sequence=VSP_055954; Note=No experimental confirmation available.; 


uniprotID: Q06732
geneSymbol: ZNF33B
reactome: R-HSA-212436;
name: Zinc finger protein 33B (Zinc finger protein 11B) (Zinc finger protein KOX2)
length: 778
go: ENSG00000196693;
snps: rs210280 rs7914982
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: O95405
geneSymbol: ZFYVE9
reactome: R-HSA-2173788;R-HSA-2173789;R-HSA-3304356;R-HSA-3315487;R-HSA-3656532;
pdb: 1DEV;1MK2;4BKW;5MJY;
length: 1425
go: ENSG00000157077;
snps: rs9803965 rs3790525 rs11809887
location: SUBCELLULAR LOCATION: Cytoplasm. Early endosome membrane.
name:
Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)

sequence:

opentargets:
cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; intracellular membrane-bounded organelle [GO:0043231]; protein-containing complex [GO:0032991]; 1-phosphatidylinositol binding [GO:0005545]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; serine-type peptidase activity [GO:0008236]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; transforming growth factor beta receptor signaling pathway [GO:0007179]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=O95405-1; Sequence=Displayed; Name=2; IsoId=O95405-2; Sequence=VSP_004315; Note=May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.; Name=3; IsoId=O95405-3; Sequence=VSP_004316, VSP_004317; 


uniprotID: Q3ZCX4
geneSymbol: ZNF568
reactome: R-HSA-212436;
name: Zinc finger protein 568
length: 644
go: ENSG00000198453;
snps: rs547483 rs1644634
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:E9PYI1}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; transcription regulatory region sequence-specific DNA binding [GO:0000976]; embryonic placenta morphogenesis [GO:0060669]; in utero embryonic development [GO:0001701]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q3ZCX4-1; Sequence=Displayed; Name=2; IsoId=Q3ZCX4-2; Sequence=VSP_028556; Name=3; IsoId=Q3ZCX4-3; Sequence=VSP_028556, VSP_046815; 


uniprotID: Q9P2E3
geneSymbol: ZNFX1
name: NFX1-type zinc finger-containing protein 1
length: 1918
go: ENSG00000124201;
snps: rs2664578 rs2273148 rs238221 rs6512577 rs36068952 rs238209
sequence:

opentargets:
chromosome, centromeric region [GO:0000775]; nuclear RNA-directed RNA polymerase complex [GO:0031380]; nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; RNA binding [GO:0003723]; zinc ion binding [GO:0008270]; chromatin silencing at centromere [GO:0030702]; chromatin silencing by small RNA [GO:0031048]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9P2E3-1; Sequence=Displayed; Name=2; IsoId=Q9P2E3-2; Sequence=VSP_002434, VSP_002435; 


uniprotID: Q06730
geneSymbol: ZNF33A
reactome: R-HSA-212436;
length: 810
go: ENSG00000189180;
snps: rs2505232 rs12256916 rs10508862
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
name:
Zinc finger protein 33A (Zinc finger and ZAK-associated protein with KRAB domain) (ZZaPK) (Zinc finger protein 11A) (Zinc finger protein KOX31)

sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q06730-1; Sequence=Displayed; Name=2; IsoId=Q06730-2; Sequence=VSP_046420; Note=No experimental confirmation available. {ECO:0000244|PubMed:28112733}; Name=3; IsoId=Q06730-3; Sequence=VSP_055165; 


uniprotID: Q6N043
geneSymbol: ZNF280D
name: Zinc finger protein 280D (Suppressor of hairy wing homolog 4) (Zinc finger protein 634)
length: 979
go: ENSG00000137871;
snps: rs28620278 rs12900993 rs12901843 rs12900729
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=6;  Name=1; IsoId=Q6N043-1; Sequence=Displayed; Name=2; IsoId=Q6N043-2; Sequence=VSP_017624; Name=3; IsoId=Q6N043-3; Sequence=VSP_017625, VSP_017626; Note=No experimental confirmation available.; Name=4; IsoId=Q6N043-4; Sequence=VSP_017623, VSP_017627, VSP_017628; Note=No experimental confirmation available.; Name=5; IsoId=Q6N043-5; Sequence=VSP_017622; Note=No experimental confirmation available.; Name=6; IsoId=Q6N043-6; Sequence=VSP_054317, VSP_054318; 


uniprotID: Q86VK4
geneSymbol: ZNF410
name: Zinc finger protein 410 (Another partner for ARF 1) (Zinc finger protein APA-1)
length: 478
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=5;  Name=1; IsoId=Q86VK4-1; Sequence=Displayed; Name=2; IsoId=Q86VK4-2; Sequence=VSP_008485, VSP_008486; Note=May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.; Name=3; IsoId=Q86VK4-3; Sequence=VSP_008487; Note=No experimental confirmation available.; Name=4; IsoId=Q86VK4-4; Sequence=VSP_042424; Note=No experimental confirmation available.; Name=5; IsoId=Q86VK4-5; Sequence=VSP_043417, VSP_043418; Note=No experimental confirmation available.; 


uniprotID: P25311
geneSymbol: AZGP1
reactome: R-HSA-5223345;
pdb: 1T7V;1T7W;1T7X;1T7Y;1T7Z;1T80;1ZAG;3ES6;
name: Zinc-alpha-2-glycoprotein (Zn-alpha-2-GP) (Zn-alpha-2-glycoprotein)
length: 298
go: ENSG00000160862;
drug: DB03721;
location: SUBCELLULAR LOCATION: Secreted.
sequence:

opentargets:
collagen-containing extracellular matrix [GO:0062023]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; protein transmembrane transporter activity [GO:0008320]; ribonuclease activity [GO:0004540]; cell adhesion [GO:0007155]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; immune response [GO:0006955]; negative regulation of cell proliferation [GO:0008285]; retina homeostasis [GO:0001895]; transmembrane transport [GO:0055085]


uniprotID: Q6P1L6
geneSymbol: ZNF343
reactome: R-HSA-212436;
name: Zinc finger protein 343
length: 599
go: ENSG00000088876;
snps: rs6049415
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q6P1L6-1; Sequence=Displayed; Name=2; IsoId=Q6P1L6-2; Sequence=VSP_016028; Note=No experimental confirmation available.; Name=3; IsoId=Q6P1L6-3; Sequence=VSP_016029, VSP_016030; Note=No experimental confirmation available.; 


uniprotID: Q6IQ21
geneSymbol: ZNF770
reactome: R-HSA-212436;
name: Zinc finger protein 770
length: 691
go: ENSG00000198146;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q5MCW4
geneSymbol: ZNF569
reactome: R-HSA-212436;
name: Zinc finger protein 569
length: 686
go: ENSG00000196437;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q5MCW4-1; Sequence=Displayed; Name=2; IsoId=Q5MCW4-2; Sequence=VSP_055966; Note=No experimental confirmation available.; 


uniprotID: Q8WXB4
geneSymbol: ZNF606
reactome: R-HSA-212436;
name: Zinc finger protein 606 (Zinc finger protein 328)
length: 792
go: ENSG00000166704;
snps: rs11673029
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15964554}.
sequence:


uniprotID: P0CI00
geneSymbol: ZNF705B
name: Putative zinc finger protein 705B
length: 300
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q9HC78
geneSymbol: ZBTB20
length: 741
go: ENSG00000181722;
snps: rs483353064 rs483353066 rs483353068 rs483353070
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8K0L9}.
name:
Zinc finger and BTB domain-containing protein 20 (Dendritic-derived BTB/POZ zinc finger protein) (Zinc finger protein 288)

sequence:

opentargets:
cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001078]; transcription regulatory region DNA binding [GO:0044212]; cellular response to glucose stimulus [GO:0071333]; lipid homeostasis [GO:0055088]; positive regulation of glycolytic process [GO:0045821]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of tumor necrosis factor production [GO:0032760]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9HC78-1; Sequence=Displayed; Name=2; IsoId=Q9HC78-2; Sequence=VSP_032503; 


uniprotID: Q9Y2G7
geneSymbol: ZFP30
reactome: R-HSA-212436;
name: Zinc finger protein 30 homolog (Zfp-30) (Zinc finger protein 745)
length: 519
go: ENSG00000120784;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q7L3S4
geneSymbol: ZNF771
reactome: R-HSA-212436;
name: Zinc finger protein 771 (Mesenchymal stem cell protein DSC43)
length: 317
snps: rs17852362
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]


uniprotID: Q9NPA5
geneSymbol: ZFP64
pdb: 1X5W;2DMD;
name: Zinc finger protein 64 homolog, isoforms 1 and 2 (Zfp-64) (Zinc finger protein 338)
length: 681
go: ENSG00000020256;
snps: rs7353222 rs6021773 rs16996517 rs3746414
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; regulation of gene expression [GO:0010468]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=6;  Name=1; IsoId=Q9NPA5-1; Sequence=Displayed; Name=2; IsoId=Q9NPA5-2; Sequence=VSP_007284; Name=3; IsoId=Q9NTW7-1; Sequence=External; Name=4; Synonyms=ZNF338; IsoId=Q9NTW7-2; Sequence=External; Name=5; IsoId=Q9NTW7-3; Sequence=External; Name=6; IsoId=Q9NTW7-4; Sequence=External; Note=Gene prediction based on EST data.; 


uniprotID: Q6AW86
geneSymbol: ZNF324B
reactome: R-HSA-212436;
name: Zinc finger protein 324B
length: 544
go: ENSG00000249471;
snps: rs12611254
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q6AW86-1; Sequence=Displayed; Name=2; IsoId=Q6AW86-2; Sequence=VSP_023658; Note=No experimental confirmation available.; 


uniprotID: Q9ULD5
geneSymbol: ZNF777
reactome: R-HSA-212436;
name: Zinc finger protein 777
length: 760
go: ENSG00000196453;
snps: rs3735318 rs3735319 rs17852167
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q9ULD5-1; Sequence=Displayed; Name=2; IsoId=Q9ULD5-2; Sequence=VSP_026559; Note=No experimental confirmation available.; Name=3; IsoId=Q9ULD5-3; Sequence=VSP_026558, VSP_026559; Note=No experimental confirmation available.; 


uniprotID: A6NM28
geneSymbol: ZFP92
name: Zinc finger protein 92 homolog (Zfp-92)
length: 416
go: ENSG00000189420;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
sequence:


uniprotID: Q14586
geneSymbol: ZNF267
reactome: R-HSA-212436;
name: Zinc finger protein 267 (Zinc finger protein HZF2)
length: 743
go: ENSG00000185947;
snps: rs7202455 rs3850114
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; multicellular organism development [GO:0007275]


uniprotID: Q9H5J0
geneSymbol: ZBTB3
name: Zinc finger and BTB domain-containing protein 3
length: 574
go: ENSG00000185670;
snps: rs544641
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]; cellular response to DNA damage stimulus [GO:0006974]


uniprotID: Q5T200
geneSymbol: ZC3H13
name: Zinc finger CCCH domain-containing protein 13
length: 1668
go: ENSG00000123200;
snps: rs9534264
sequence:

opentargets:
nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; RNA N6-methyladenosine methyltransferase complex [GO:0036396]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; mRNA methylation [GO:0080009]; mRNA processing [GO:0006397]; multicellular organism development [GO:0007275]; regulation of stem cell population maintenance [GO:2000036]; RNA splicing [GO:0008380]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q5T200-1; Sequence=Displayed; Note=Gene prediction confirmed by EST data.; Name=2; IsoId=Q5T200-2; Sequence=VSP_027202, VSP_014252, VSP_014253; 

location:
SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000269|PubMed:24100041}. Nucleus, nucleoplasm {ECO:0000269|PubMed:24100041}.


uniprotID: A4D1E1
geneSymbol: ZNF804B
reactome: R-HSA-212436;
name: Zinc finger protein 804B
length: 1349
go: ENSG00000182348;
opentargets: metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
snps: rs1916830 rs801840 rs10487075 rs59859857 rs56948780 rs6963781 rs801841
sequence:


uniprotID: Q494X3
geneSymbol: ZNF404
name: Zinc finger protein 404
length: 552
go: ENSG00000176222;
snps: rs12977303 rs239942
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q96K83
geneSymbol: ZNF521
reactome: R-HSA-8940973;
name: Zinc finger protein 521 (Early hematopoietic zinc finger protein) (LYST-interacting protein 3)
length: 1311
go: ENSG00000198795;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904]; neuron fate commitment [GO:0048663]


uniprotID: Q6PK81
geneSymbol: ZNF773
reactome: R-HSA-212436;
name: Zinc finger protein 773 (Zinc finger protein 419B)
length: 442
go: ENSG00000152439;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q6PK81-1; Sequence=Displayed; Name=2; IsoId=Q6PK81-2; Sequence=VSP_024870; Note=No experimental confirmation available.; 


uniprotID: P0CG31
geneSymbol: ZNF286B
name: Putative zinc finger protein 286B
length: 522
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q9Y5A9
geneSymbol: YTHDF2
pdb: 4RDN;4RDO;4WQN;
length: 579
snps: rs16838382 rs35288745
name:
YTH domain-containing family protein 2 (CLL-associated antigen KW-14) (High-glucose-regulated protein 8) (Renal carcinoma antigen NY-REN-2)

sequence:

opentargets:
cytoplasmic ribonucleoprotein granule [GO:0036464]; cytosol [GO:0005829]; microtubule organizing center [GO:0005815]; nucleus [GO:0005634]; P-body [GO:0000932]; N6-methyladenosine-containing RNA binding [GO:1990247]; RNA binding [GO:0003723]; embryonic morphogenesis [GO:0048598]; endothelial to hematopoietic transition [GO:0098508]; humoral immune response [GO:0006959]; mRNA destabilization [GO:0061157]; negative regulation of Notch signaling pathway [GO:0045746]; oocyte maturation [GO:0001556]; positive regulation of cap-independent translational initiation [GO:1903679]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of meiotic cell cycle process involved in oocyte maturation [GO:1903538]; regulation of mRNA stability [GO:0043488]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9Y5A9-1; Sequence=Displayed; Name=2; IsoId=Q9Y5A9-2; Sequence=VSP_009297; Note=May be due to intron retention. No experimental confirmation available.; 

location:
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:26458103}. Nucleus {ECO:0000269|PubMed:26458103}. Cytoplasm, P-body {ECO:0000269|PubMed:24284625}. Note=Localizes to the cytosol and relocates to the nucleus following heat shock stress (PubMed:26458103). {ECO:0000269|PubMed:26458103}.


uniprotID: Q76KX8
geneSymbol: ZNF534
name: Zinc finger protein 534 (KRAB domain only protein 3)
length: 674
go: ENSG00000198633;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q76KX8-1; Sequence=Displayed; Name=2; IsoId=Q76KX8-2; Sequence=VSP_039177; 


uniprotID: Q9NSJ1
geneSymbol: ZNF355P
name: Putative zinc finger protein 355P (Zinc finger protein ZnFP01)
length: 428
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q8N8Y5
geneSymbol: ZFP41
name: Zinc finger protein 41 homolog (Zfp-41)
length: 198
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
sequence:
MEKPAGRKKKTPTPREEADVQKSALREEKVSGDRKPPERPTVPRKPRTEPCLSPEDEEHVFDAFDASFKDDFEGVPVFIPFQRKKPYECSECGRIFKHKTDHIRHQRVHTGEKPFKCAQCGKAFRHSSDVTKHQRTHTGEKPFKCGECGKAFNCGSNLLKHQKTHTGEKPYECTHCGKAFAYSSCLIRHQKRHPRKKP

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; cell differentiation [GO:0030154]; multicellular organism development [GO:0007275]; spermatogenesis [GO:0007283]


uniprotID: Q9NQZ6
geneSymbol: ZC4H2
name: Zinc finger C4H2 domain-containing protein (Hepatocellular carcinoma-associated antigen 127)
length: 224
go: ENSG00000126970;
snps: rs398122938 rs1057520297 rs879255235 rs398122939 rs879255236
sequence:

opentargets:
cell junction [GO:0030054]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; postsynaptic membrane [GO:0045211]; metal ion binding [GO:0046872]; nervous system development [GO:0007399]; neuromuscular junction development [GO:0007528]; positive regulation of neuron differentiation [GO:0045666]; spinal cord motor neuron differentiation [GO:0021522]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=5;  Name=1; IsoId=Q9NQZ6-1; Sequence=Displayed; Name=2; IsoId=Q9NQZ6-2; Sequence=VSP_008517, VSP_008518; Note=No experimental confirmation available.; Name=3; IsoId=Q9NQZ6-3; Sequence=VSP_013469; Note=No experimental confirmation available.; Name=4; IsoId=Q9NQZ6-4; Sequence=VSP_042513; Note=No experimental confirmation available.; Name=5; IsoId=Q9NQZ6-5; Sequence=VSP_047588; Note=No experimental confirmation available.; 

location:
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:23623388}. Nucleus {ECO:0000269|PubMed:23623388, ECO:0000269|PubMed:26056227}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000269|PubMed:23623388}. Note=Upon transfection into mouse primary hippocampal neurons, localizes at excitatory, but not inhibitory, postsynaptic sites.


uniprotID: O15209
geneSymbol: ZBTB22
length: 634
go: ENSG00000236104;
snps: rs35663442 rs3130100
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
name:
Zinc finger and BTB domain-containing protein 22 (Protein BING1) (Zinc finger and BTB domain-containing protein 22A) (Zinc finger protein 297)

sequence:


uniprotID: P17041
geneSymbol: ZNF32
pdb: 2EPC;2EPT;2EPU;2YTA;2YTB;
name: Zinc finger protein 32 (C2H2-546) (Zinc finger protein KOX30)
length: 273
go: ENSG00000169740;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q86UE3
geneSymbol: ZNF546
reactome: R-HSA-212436;
name: Zinc finger protein 546 (Zinc finger protein 49)
length: 836
go: ENSG00000187187;
snps: rs17854378 rs2111543 rs2111544 rs17710336 rs12460371 rs7255186 rs12373540
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q8NEM1
geneSymbol: ZNF680
reactome: R-HSA-212436;
name: Zinc finger protein 680
length: 530
go: ENSG00000173041;
snps: rs11768951 rs17856885 rs17852813
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q8NEM1-1; Sequence=Displayed; Name=2; IsoId=Q8NEM1-2; Sequence=VSP_043114, VSP_043115; Note=No experimental confirmation available.; 


uniprotID: Q96K80
geneSymbol: ZC3H10
name: Zinc finger CCCH domain-containing protein 10
length: 434
go: ENSG00000135482;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:28431233}.
sequence:

opentargets:
cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; metal ion binding [GO:0046872]; miRNA binding [GO:0035198]; RNA binding [GO:0003723]; negative regulation of production of miRNAs involved in gene silencing by miRNA [GO:1903799]; posttranscriptional regulation of gene expression [GO:0010608]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]


uniprotID: Q8TAF7
geneSymbol: ZNF461
reactome: R-HSA-212436;
name: Zinc finger protein 461 (Gonadotropin-inducible ovary transcription repressor 1) (GIOT-1)
length: 563
go: ENSG00000197808;
snps: rs10419469
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q8TAF7-1; Sequence=Displayed; Name=2; IsoId=Q8TAF7-2; Sequence=VSP_011396; Note=No experimental confirmation available.; 


uniprotID: Q9HBT8
geneSymbol: ZNF286A
reactome: R-HSA-212436;
name: Zinc finger protein 286A
length: 521
go: ENSG00000187607;
snps: rs3760299
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9HBT8-1; Sequence=Displayed; Name=2; IsoId=Q9HBT8-2; Sequence=VSP_056673; Note=No experimental confirmation available.; 


uniprotID: A6NP61
geneSymbol: ZAR1L
name: ZAR1-like protein
length: 321
go: ENSG00000189167;
opentargets: cytoplasm [GO:0005737]
sequence:


uniprotID: Q8NEW0
geneSymbol: SLC30A7
reactome: R-HSA-264876;R-HSA-435368;
name: Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7) (Znt-like transporter 2)
length: 376
go: ENSG00000162695;
sequence:

opentargets:
cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; perinuclear region of cytoplasm [GO:0048471]; vesicle [GO:0031982]; cation transmembrane transporter activity [GO:0008324]; sequestering of zinc ion [GO:0032119]; zinc ion transport [GO:0006829]

location:
SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:12446736}; Multi-pass membrane protein {ECO:0000269|PubMed:12446736}.


uniprotID: Q63HK3
geneSymbol: ZKSCAN2
name: Zinc finger protein with KRAB and SCAN domains 2 (Zinc finger protein 694)
length: 967
snps: rs2112811 rs8059494 rs7197424
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q63HK3-1; Sequence=Displayed; Name=2; IsoId=Q63HK3-2; Sequence=VSP_018189, VSP_018190; Note=No experimental confirmation available.; 


uniprotID: O75152
geneSymbol: ZC3H11A
reactome: R-HSA-109688;R-HSA-159236;R-HSA-72187;
name: Zinc finger CCCH domain-containing protein 11A
length: 810
go: ENSG00000058673;ENSG00000257315;
snps: rs11240604
sequence:

opentargets:
nucleoplasm [GO:0005654]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; mRNA binding [GO:0003729]; RNA binding [GO:0003723]; mRNA 3'-end processing [GO:0031124]; mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA export from nucleus [GO:0006405]


uniprotID: P17038
geneSymbol: ZNF43
reactome: R-HSA-212436;
length: 809
go: ENSG00000198521;
snps: rs200399581 rs1063327
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
name:
Zinc finger protein 43 (Zinc finger protein 39) (Zinc finger protein HTF6) (Zinc finger protein KOX27)

sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=P17038-1; Sequence=Displayed; Name=2; IsoId=P17038-2; Sequence=VSP_036734; 


uniprotID: Q8TD23
geneSymbol: ZNF675
reactome: R-HSA-212436;
name: Zinc finger protein 675 (TRAF6-binding zinc finger protein) (TRAF6-inhibitory zinc finger protein)
length: 568
go: ENSG00000197372;
snps: rs4380159 rs11671053 rs73029758
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; ubiquitin protein ligase binding [GO:0031625]; zinc ion binding [GO:0008270]; bone resorption [GO:0045453]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of interleukin-1-mediated signaling pathway [GO:2000660]; negative regulation of JNK cascade [GO:0046329]; negative regulation of JUN kinase activity [GO:0043508]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]


uniprotID: Q9NPG8
geneSymbol: ZDHHC4
length: 344
go: ENSG00000136247;
snps: rs11559146
name:
Probable palmitoyltransferase ZDHHC4 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 4) (DHHC-4) (Zinc finger protein 374)

sequence:

opentargets:
endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein targeting to membrane [GO:0006612]

location:
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000269|PubMed:21926431}; Multi-pass membrane protein {ECO:0000255}.


uniprotID: C9JN71
geneSymbol: ZNF878
name: Zinc finger protein 878
length: 531
go: ENSG00000257446;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q7Z2F6
geneSymbol: ZNF720
reactome: R-HSA-212436;
name: Putative protein ZNF720
length: 126
go: ENSG00000197302;
sequence:
MGLLTFRDVAIEFSREEWEHLDSDQKLLYGDVMLENYGNLVSLGLAVSKPDLITFLEQRKEPWNVKSAETVAIQPDIFSHDTQGLLRKKLIEASFQKVILDGYGSCGPQNLNLRKEWESEGKIILW

opentargets:
intracellular [GO:0005622]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; nucleic acid binding [GO:0003676]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q7Z2F6-1; Sequence=Displayed; Name=2; IsoId=Q7Z2F6-2; Sequence=VSP_033024, VSP_033025, VSP_033026; Note=No experimental confirmation available.; 


uniprotID: Q2M1K9
geneSymbol: ZNF423
pdb: 2MDG;
length: 1284
go: ENSG00000102935;
snps: rs34214571 rs200585917
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10660046}.
name:
Zinc finger protein 423 (Olf1/EBF-associated zinc finger protein) (hOAZ) (Smad- and Olf-interacting zinc finger protein)

sequence:

opentargets:
nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; cell differentiation [GO:0030154]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of transcription, DNA-templated [GO:0045892]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription, DNA-templated [GO:0006355]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q2M1K9-1; Sequence=Displayed; Name=2; IsoId=Q2M1K9-2; Sequence=VSP_057595; Note=No experimental confirmation available. {ECO:0000305}; 


uniprotID: P15621
geneSymbol: ZNF44
length: 663
go: ENSG00000197857;
snps: rs11882046 rs11879168
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
name:
Zinc finger protein 44 (Gonadotropin-inducible ovary transcription repressor 2) (GIOT-2) (Zinc finger protein 55) (Zinc finger protein 58) (Zinc finger protein KOX7)

sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=P15621-1; Sequence=Displayed; Name=2; IsoId=P15621-2; Sequence=VSP_035757, VSP_035758, VSP_035759; Name=3; IsoId=P15621-3; Sequence=VSP_035759; 


uniprotID: Q9H171
geneSymbol: ZBP1
reactome: R-HSA-1606322;R-HSA-1606341;R-HSA-1810476;R-HSA-3134975;
pdb: 2L4M;2LNB;3EYI;4KA4;
name: Z-DNA-binding protein 1 (Tumor stroma and activated macrophage protein DLM-1)
length: 429
go: ENSG00000124256;
snps: rs35813125 rs35895307 rs34964609 rs2073145 rs16981187 rs34478944 rs2865394 rs41275648
sequence:

opentargets:
cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; DNA binding [GO:0003677]; double-stranded RNA adenosine deaminase activity [GO:0003726]; identical protein binding [GO:0042802]; left-handed Z-DNA binding [GO:0003692]; RNA binding [GO:0003723]; innate immune response [GO:0045087]; positive regulation of type I interferon production [GO:0032481]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; regulation of type I interferon production [GO:0032479]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=7;  Comment=Additional isoforms seem to exist.; Name=1; IsoId=Q9H171-1; Sequence=Displayed; Name=2; IsoId=Q9H171-2; Sequence=VSP_004081; Name=3; IsoId=Q9H171-3; Sequence=VSP_004082; Name=4; IsoId=Q9H171-4; Sequence=VSP_004078; Name=5; IsoId=Q9H171-5; Sequence=VSP_004079, VSP_004080; Name=6; IsoId=Q9H171-6; Sequence=VSP_045405, VSP_045406; Note=No experimental confirmation available.; Name=7; IsoId=Q9H171-7; Sequence=VSP_046081; Note=No experimental confirmation available.; 


uniprotID: Q8NAM6
geneSymbol: ZSCAN4
name: Zinc finger and SCAN domain-containing protein 4 (Zinc finger protein 494)
length: 433
go: ENSG00000180532;
snps: rs11668570
sequence:

opentargets:
nuclear chromosome, telomeric region [GO:0000784]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; negative regulation of mitotic recombination [GO:0045950]; regulation of transcription by RNA polymerase II [GO:0006357]; telomere maintenance via telomere lengthening [GO:0010833]

location:
SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}. Chromosome, telomere {ECO:0000250}.


uniprotID: Q96NI8
geneSymbol: ZNF570
reactome: R-HSA-212436;
name: Zinc finger protein 570
length: 536
go: ENSG00000171827;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q96NI8-1; Sequence=Displayed; Name=2; IsoId=Q96NI8-2; Sequence=VSP_055967; Note=No experimental confirmation available.; 


uniprotID: Q8TCF1
geneSymbol: ZFAND1
name: AN1-type zinc finger protein 1 (Zinc finger AN1-type-containing protein 1)
length: 268
go: ENSG00000104231;
sequence:

opentargets:
cytoplasmic stress granule [GO:0010494]; proteasome binding [GO:0070628]; zinc ion binding [GO:0008270]; cellular response to arsenite ion [GO:1903843]; positive regulation of intracellular protein transport [GO:0090316]; stress granule disassembly [GO:0035617]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=4;  Name=1; IsoId=Q8TCF1-1; Sequence=Displayed; Name=2; IsoId=Q8TCF1-2; Sequence=VSP_014988; Note=No experimental confirmation available.; Name=3; IsoId=Q8TCF1-3; Sequence=VSP_046404; Note=No experimental confirmation available.; Name=4; IsoId=Q8TCF1-4; Sequence=VSP_054080, VSP_054081; 

location:
SUBCELLULAR LOCATION: Cytoplasm, Stress granule {ECO:0000269|PubMed:29804830}. Note=Colocalizes with TIA1, G3BP1, VCP and 26S proteasome in cytoplasmic stress granules (SGs) in response to arsenite-induced stress treatment in a VCP-independent manner (PubMed:29804830). Not localized in SGs in response to other heat- oxidative- or osmotic-induced stress treatments. Colocalizes with VCP in cytoplasmic speckles (PubMed:29804830). {ECO:0000269|PubMed:29804830}.


uniprotID: Q05996
geneSymbol: ZP2
reactome: R-HSA-1300644;
length: 745
go: ENSG00000103310;
snps: rs2075520
name:
Zona pellucida sperm-binding protein 2 (Zona pellucida glycoprotein 2) (Zp-2) (Zona pellucida protein A) [Cleaved into: Processed zona pellucida sperm-binding protein 2]

sequence:

opentargets:
collagen-containing extracellular matrix [GO:0062023]; endoplasmic reticulum [GO:0005783]; extracellular region [GO:0005576]; integral component of membrane [GO:0016021]; multivesicular body [GO:0005771]; plasma membrane [GO:0005886]; acrosin binding [GO:0032190]; coreceptor activity [GO:0015026]; identical protein binding [GO:0042802]; binding of sperm to zona pellucida [GO:0007339]; prevention of polyspermy [GO:0060468]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q05996-1; Sequence=Displayed; Name=2; IsoId=Q05996-2; Sequence=VSP_054508; Note=No experimental confirmation available.; 

location:
SUBCELLULAR LOCATION: Processed zona pellucida sperm-binding protein 2: Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P20239}. Note=The glycoproteinaceous translucent extracellular matrix that surrounds the mammalian oocyte is called zona pellucida. {ECO:0000250|UniProtKB:P20239}.; SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P20239}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P20239}.


uniprotID: Q09FC8
geneSymbol: ZNF415
reactome: R-HSA-212436;
name: Zinc finger protein 415
length: 603
go: ENSG00000170954;
snps: rs16984466 rs1054485 rs1133327 rs1560099 rs10410030
sequence:

opentargets:
cytoplasm [GO:0005737]; fibrillar center [GO:0001650]; microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=6;  Name=1; Synonyms=ZNF415-3; IsoId=Q09FC8-1; Sequence=Displayed; Name=2; Synonyms=ZNF415-2; IsoId=Q09FC8-2; Sequence=VSP_025178; Name=3; Synonyms=ZNF415-1; IsoId=Q09FC8-3; Sequence=VSP_025175; Name=4; Synonyms=ZNF415-4; IsoId=Q09FC8-4; Sequence=VSP_025177; Name=5; Synonyms=ZNF415-5; IsoId=Q09FC8-5; Sequence=VSP_025176; Name=6; IsoId=Q09FC8-6; Sequence=VSP_044807; Note=No experimental confirmation available.; 

location:
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17055453}. Cytoplasm {ECO:0000269|PubMed:17055453}. Note=Isoforms 1, isoform 2, isoform 4 and isoform 5 showed both nuclear and cytoplasm localization. Isoform 3 localized only to nucleus.


uniprotID: Q9H900
geneSymbol: ZWILCH
reactome: R-HSA-141444;R-HSA-2467813;R-HSA-2500257;R-HSA-5663220;R-HSA-68877;
pdb: 3IF8;
name: Protein zwilch homolog (hZwilch)
length: 591
go: ENSG00000174442;
snps: rs11071896
location: SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore {ECO:0000269|PubMed:20462495}.
sequence:

opentargets:
condensed chromosome kinetochore [GO:0000777]; cytosol [GO:0005829]; kinetochore [GO:0000776]; RZZ complex [GO:1990423]; cell division [GO:0051301]; mitotic cell cycle checkpoint [GO:0007093]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9H900-1; Sequence=Displayed; Name=2; IsoId=Q9H900-2; Sequence=VSP_030365; 


uniprotID: P0DPD5
geneSymbol: ZNF723
name: Zinc finger protein 723
length: 513
go: ENSG00000268696;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q9HCK0
geneSymbol: ZBTB26
length: 441
go: ENSG00000171448;
snps: rs7856488
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
name:
Zinc finger and BTB domain-containing protein 26 (Zinc finger protein 481) (Zinc finger protein Bioref)

sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; metal ion binding [GO:0046872]


uniprotID: P0DKX0
geneSymbol: ZNF728
name: Zinc finger protein 728
length: 622
go: ENSG00000269067;
sequence:

opentargets:
intracellular [GO:0005622]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; regulation of transcription, DNA-templated [GO:0006355]


uniprotID: Q6ZMV8
geneSymbol: ZNF730
reactome: R-HSA-212436;
name: Putative zinc finger protein 730
length: 503
go: ENSG00000183850;
snps: rs7247102
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
sequence:


uniprotID: A8MT66
name: Putative uncharacterized protein ENSP00000383407
length: 165
sequence:
MNLFCISLEGSMDSLYEPIPEQQANQENMSSRTDSPIPPFGESEQTPNNLFVGVSNLENAKPKKRKLFRRFMSENKIFEGKTVNDKIWQEHSKHKNDSHIRRPCQLKDLNENDFLSNNIHTYQGKTLQGTSYQVTSECWSPFHYQRHVETTVDELVRHFFPDVTI


uniprotID: A8MWP4
name: Putative uncharacterized protein ENSP00000401716
length: 228
sequence:


uniprotID: P0C7U3
geneSymbol: ZDHHC11B
length: 371
go: ENSG00000206077;
snps: rs1809933 rs634901 rs3817063
location: SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
name:
Probable palmitoyltransferase ZDHHC11B (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 11B) (DHHC-11B)

sequence:

opentargets:
endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein targeting to membrane [GO:0006612]


uniprotID: Q86XF7
geneSymbol: ZNF575
name: Zinc finger protein 575
length: 245
go: ENSG00000176472;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: O60315
geneSymbol: ZEB2
pdb: 2DA7;
length: 1214
go: ENSG00000169554;
snps: rs137852983
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16061479, ECO:0000269|PubMed:9853615}.
name:
Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (SMADIP1) (Zinc finger homeobox protein 1b)

sequence:

opentargets:
cytosol [GO:0005829]; nuclear chromatin [GO:0000790]; nucleolus [GO:0005730]; nucleus [GO:0005634]; distal enhancer DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001205]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; phosphatase regulator activity [GO:0019208]; R-SMAD binding [GO:0070412]; sequence-specific DNA binding [GO:0043565]; cell proliferation in forebrain [GO:0021846]; collateral sprouting [GO:0048668]; corpus callosum morphogenesis [GO:0021540]; corticospinal tract morphogenesis [GO:0021957]; developmental pigmentation [GO:0048066]; hippocampus development [GO:0021766]; mammillary axonal complex development [GO:0061373]; melanocyte migration [GO:0097324]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; neural crest cell migration [GO:0001755]; neural tube closure [GO:0001843]; positive regulation of axonogenesis [GO:0050772]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of lens fiber cell differentiation [GO:1902748]; positive regulation of melanin biosynthetic process [GO:0048023]; positive regulation of melanocyte differentiation [GO:0045636]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of melanosome organization [GO:1903056]; somitogenesis [GO:0001756]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=O60315-1; Sequence=Displayed; Name=2; IsoId=O60315-2; Sequence=VSP_044797; Note=No experimental confirmation available.; 


uniprotID: Q9P243
geneSymbol: ZFAT
name: Zinc finger protein ZFAT (Zinc finger gene in AITD susceptibility region) (Zinc finger protein 406)
length: 1243
go: ENSG00000066827;
snps: rs17778003 rs12541381 rs35003767
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}.
pdb:
2ELM;2ELN;2ELO;2ELP;2ELQ;2ELR;2ELS;2ELT;2ELU;2ELV;2RSH;2RSI;2RSJ;2RUT;2RUU;2RUV;2RUW;2RUX;2RUY;2RUZ;2RV0;2RV1;2RV2;2RV3;2RV6;2RV7;

sequence:

opentargets:
cytosol [GO:0005829]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001077]; hematopoietic progenitor cell differentiation [GO:0002244]; regulation of transcription, DNA-templated [GO:0006355]; spongiotrophoblast layer development [GO:0060712]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=4;  Name=1; Synonyms=ZFAT-1; IsoId=Q9P243-1; Sequence=Displayed; Name=2; Synonyms=ZFAT-2, ZFAT-3; IsoId=Q9P243-2; Sequence=VSP_016959; Name=3; Synonyms=TR-ZFAT; IsoId=Q9P243-3; Sequence=VSP_016959, VSP_034938, VSP_034939; Name=4; IsoId=Q9P243-4; Sequence=VSP_045461; Note=No experimental confirmation available.; 


uniprotID: Q9NS37
geneSymbol: CREBZF
length: 354
go: ENSG00000137504;
name:
CREB/ATF bZIP transcription factor (Host cell factor-binding transcription factor Zhangfei) (HCF-binding transcription factor Zhangfei)

sequence:

opentargets:
mitochondrion [GO:0005739]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; identical protein binding [GO:0042802]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of transcription, DNA-templated [GO:0045892]; regulation of DNA-binding transcription factor activity [GO:0051090]; response to virus [GO:0009615]; transcription, DNA-templated [GO:0006351]

location:
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15705566}. Note=Colocalizes in promyelocytic leukemia protein nuclear bodies (PML-NB) with CREB3 and HCFC1.


uniprotID: Q96C00
geneSymbol: ZBTB9
name: Zinc finger and BTB domain-containing protein 9
length: 473
go: ENSG00000213588;
opentargets: nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]
snps: rs9469425
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q8NHY6
geneSymbol: ZFP28
reactome: R-HSA-212436;
pdb: 2EM2;2EM3;2EM4;2EMJ;2EMK;2EML;2EN9;2ENH;2EOH;2EP0;2EPX;2EPZ;2YTM;
name: Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6)
length: 868
go: ENSG00000196867;
snps: rs34136271 rs10409531
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q8NHY6-1; Sequence=Displayed; Name=2; IsoId=Q8NHY6-2; Sequence=VSP_055934, VSP_055935; Note=No experimental confirmation available. {ECO:0000305}; 


uniprotID: Q8N883
geneSymbol: ZNF614
reactome: R-HSA-212436;
name: Zinc finger protein 614
length: 585
go: ENSG00000142556;
snps: rs9636139 rs45596739 rs35098634 rs8104890
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q8N883-1; Sequence=Displayed; Name=2; IsoId=Q8N883-2; Sequence=VSP_056549, VSP_056550; Note=No experimental confirmation available.; 


uniprotID: Q19AV6
geneSymbol: ZSWIM7
length: 140
go: ENSG00000214941;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
name:
Zinc finger SWIM domain-containing protein 7 (SWIM domain-containing and Srs2-interacting protein 1 homolog) (SWIM-type zinc finger domain-containing protein 7)

sequence:
MAVVLPAVVEELLSEMAAAVQESARIPDEYLLSLKFLFGSSATQALDLVDRQSITLISSPSGRRVYQVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

opentargets:
nucleus [GO:0005634]; Shu complex [GO:0097196]; zinc ion binding [GO:0008270]; double-strand break repair via homologous recombination [GO:0000724]; protein stabilization [GO:0050821]


uniprotID: Q8TAQ5
geneSymbol: ZNF420
reactome: R-HSA-212436;R-HSA-6803204;
name: Zinc finger protein 420
length: 688
go: ENSG00000197050;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleoplasm [GO:0005654]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; regulation of apoptotic process [GO:0042981]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q8TAQ5-1; Sequence=Displayed; Name=2; IsoId=Q8TAQ5-2; Sequence=VSP_055951, VSP_055952; Note=No experimental confirmation available.; 


uniprotID: Q499Z4
geneSymbol: ZNF672
name: Zinc finger protein 672
length: 452
go: ENSG00000171161;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q499Z4-1; Sequence=Displayed; Name=2; IsoId=Q499Z4-2; Sequence=VSP_018161, VSP_018162; Note=No experimental confirmation available.; 


uniprotID: Q6ZSS3
geneSymbol: ZNF621
reactome: R-HSA-212436;
name: Zinc finger protein 621
length: 439
go: ENSG00000172888;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nuclear speck [GO:0016607]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q6ZSS3-1; Sequence=Displayed; Name=2; IsoId=Q6ZSS3-2; Sequence=VSP_016041, VSP_016042; Note=No experimental confirmation available.; 


uniprotID: Q86TI4
geneSymbol: WDR86
name: WD repeat-containing protein 86
length: 376
go: ENSG00000187260;
snps: rs4141455
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=4;  Name=3; IsoId=Q86TI4-3; Sequence=Displayed; Name=1; IsoId=Q86TI4-1; Sequence=VSP_039818; Note=No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.; Name=2; IsoId=Q86TI4-2; Sequence=VSP_031725, VSP_031726; Note=No experimental confirmation available.; Name=4; IsoId=Q86TI4-4; Sequence=VSP_054908; Note=No experimental confirmation available. {ECO:0000305}; 


uniprotID: Q9H0M0
geneSymbol: WWP1
reactome: R-HSA-1253288;R-HSA-2672351;R-HSA-8939902;R-HSA-983168;
pdb: 1ND7;2OP7;5HPS;5HPT;
length: 922
go: ENSG00000123124;
name:
NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 2.3.2.26) (Atrophin-1-interacting protein 5) (AIP5) (HECT-type E3 ubiquitin transferase WWP1) (TGIF-interacting ubiquitin ligase 1) (Tiul1) (WW domain-containing protein 1)

sequence:

opentargets:
cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ubiquitin ligase complex [GO:0000151]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842]; central nervous system development [GO:0007417]; ion transmembrane transport [GO:0034220]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of protein catabolic process [GO:0045732]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]; viral entry into host cell [GO:0046718]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=6;  Comment=Additional isoforms seem to exist.; Name=1; Synonyms=A; IsoId=Q9H0M0-1; Sequence=Displayed; Name=2; Synonyms=B; IsoId=Q9H0M0-2; Sequence=VSP_007601, VSP_007603; Name=3; Synonyms=C; IsoId=Q9H0M0-3; Sequence=VSP_007602; Name=4; Synonyms=D; IsoId=Q9H0M0-4; Sequence=Not described; Name=5; Synonyms=E; IsoId=Q9H0M0-5; Sequence=Not described; Name=6; Synonyms=F; IsoId=Q9H0M0-6; Sequence=VSP_007600; 

location:
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus {ECO:0000250}.


uniprotID: Q96KV7
geneSymbol: WDR90
name: WD repeat-containing protein 90
length: 1748
go: ENSG00000161996;
opentargets: centriole [GO:0005814]; cilium assembly [GO:0060271]
snps: rs13337278 rs11642546 rs3803697 rs4984906 rs7190775 rs11866949
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=5;  Name=1; IsoId=Q96KV7-1; Sequence=Displayed; Note=Gene prediction based on partial mRNA and EST data.; Name=2; IsoId=Q96KV7-10; Sequence=VSP_034290, VSP_034303, VSP_041087, VSP_041088; Note=No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. {ECO:0000305}; Name=3; IsoId=Q96KV7-3; Sequence=VSP_034298, VSP_034300; Note=No experimental confirmation available. {ECO:0000305}; Name=4; IsoId=Q96KV7-7; Sequence=VSP_034290, VSP_034303, VSP_034306; Note=No experimental confirmation available.; Name=5; IsoId=Q96KV7-5; Sequence=VSP_034294, VSP_034298, VSP_034300; Note=No experimental confirmation available. {ECO:0000305}; 

location:
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:28781053}.


uniprotID: Q6ZS92
name: Putative uncharacterized protein FLJ45721
length: 163
sequence:
MCMNTSIHAHTYARTHTHSVFMSSNVTVFQWMRLMRASSRSFTQAIPAGQLLQTACSHLFTTQNTCQNALGNNTRLQHTEKVRLSIGLADFGLPGIARNTFVVPDSISRYCREGSVIGKCCPSRKSALLNKQGSLKKFKITRGETQPGVTISVLELAEIDQRF


uniprotID: A6NL46
name: Putative UPF0607 protein ENSP00000332738
length: 340
sequence:


uniprotID: Q96TA2
geneSymbol: YME1L1
reactome: R-HSA-8949664;
length: 773
go: ENSG00000136758;
snps: rs1057519312
name:
ATP-dependent zinc metalloprotease YME1L1 (EC 3.4.24.-) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin-associated metalloprotease) (PAMP) (YME1-like protein 1)

sequence:

opentargets:
integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nuclear body [GO:0016604]; ATP binding [GO:0005524]; ATP-dependent peptidase activity [GO:0004176]; metal ion binding [GO:0046872]; metalloendopeptidase activity [GO:0004222]; cell proliferation [GO:0008283]; mitochondrial protein catabolic process [GO:0035694]; mitochondrial protein processing [GO:0034982]; mitochondrion organization [GO:0007005]; negative regulation of apoptotic process [GO:0043066]; protein hexamerization [GO:0034214]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515]; proteolysis [GO:0006508]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q96TA2-1; Sequence=Displayed; Name=2; IsoId=Q96TA2-2; Sequence=VSP_010017; Note=Mutagenesis of Glu-543 to Gln does not complement excessive accumulation of subunits (NDUFB6, COX4,ND1) due to YME1 deletion mutant. Probably has no ATPase activity.; Name=3; IsoId=Q96TA2-3; Sequence=VSP_010017, VSP_045336; 

location:
SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:10843804, ECO:0000269|PubMed:22262461}. Mitochondrion {ECO:0000269|PubMed:26923599, ECO:0000269|PubMed:27495975}.


uniprotID: P49750
geneSymbol: YLPM1
name: YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113)
length: 2146
go: ENSG00000119596;
sequence:

opentargets:
cytosol [GO:0005829]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; RNA binding [GO:0003723]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=4; IsoId=P49750-4; Sequence=Displayed; Name=3; IsoId=P49750-3; Sequence=VSP_059470, VSP_059471, VSP_059472; Name=1; IsoId=P49750-1; Sequence=VSP_059470; 

location:
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17890166}. Nucleus speckle {ECO:0000250}. Note=Migrates to nucleolar caps upon blockage of transcription.


uniprotID: Q4V348
geneSymbol: ZNF658B
reactome: R-HSA-212436;
name: Zinc finger protein 658B
length: 819
opentargets: nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: P08048
geneSymbol: ZFY
pdb: 1KLR;1KLS;1XRZ;5ZNF;7ZNF;
name: Zinc finger Y-chromosomal protein
length: 801
go: ENSG00000067646;
drug: DB02884;DB05483;
location: SUBCELLULAR LOCATION: Nucleus.
sequence:

opentargets:
nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=P08048-1; Sequence=Displayed; Name=2; IsoId=P08048-2; Sequence=VSP_042774, VSP_042775; Note=No experimental confirmation available.; Name=3; IsoId=P08048-3; Sequence=VSP_042824, VSP_042825, VSP_042826; Note=No experimental confirmation available.; 


uniprotID: O95125
geneSymbol: ZNF202
reactome: R-HSA-212436;
name: Zinc finger protein 202 (Zinc finger protein with KRAB and SCAN domains 10)
length: 648
go: ENSG00000166261;
snps: rs1144507 rs34111365
location: SUBCELLULAR LOCATION: Nucleus.
sequence:

opentargets:
nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001078]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; lipid metabolic process [GO:0006629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; transcription by RNA polymerase II [GO:0006366]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=Beta; Synonyms=2; IsoId=O95125-1; Sequence=Displayed; Name=Alpha; Synonyms=1; IsoId=O95125-2; Sequence=VSP_006902; 


uniprotID: Q9NSD4
geneSymbol: ZNF275
name: Zinc finger protein 275
length: 429
go: ENSG00000063587;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9NSD4-1; Sequence=Displayed; Name=2; IsoId=Q9NSD4-2; Sequence=VSP_055944; Note=No experimental confirmation available.; 


uniprotID: Q96MP5
geneSymbol: ZSWIM3
name: Zinc finger SWIM domain-containing protein 3
length: 696
go: ENSG00000132801;
opentargets: zinc ion binding [GO:0008270]
snps: rs2903808 rs35928298
sequence:


uniprotID: Q6ZMW2
geneSymbol: ZNF782
reactome: R-HSA-212436;
name: Zinc finger protein 782
length: 699
go: ENSG00000196597;
snps: rs7870376 rs4645656 rs34763627 rs35403084
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q96T25
geneSymbol: ZIC5
name: Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5)
length: 663
go: ENSG00000139800;
snps: rs201876139
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; cell differentiation [GO:0030154]; nervous system development [GO:0007399]


uniprotID: Q03936
geneSymbol: ZNF92
reactome: R-HSA-212436;
name: Zinc finger protein 92 (Zinc finger protein HTF12)
length: 586
go: ENSG00000146757;
snps: rs10265083 rs17853615 rs10239197
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; zinc ion binding [GO:0008270]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q03936-1; Sequence=Displayed; Name=2; IsoId=Q03936-2; Sequence=VSP_016964; Note=No experimental confirmation available.; Name=3; IsoId=Q03936-3; Sequence=VSP_016965; Note=No experimental confirmation available.; 


uniprotID: Q9H4Z2
geneSymbol: ZNF335
reactome: R-HSA-5617472;
name: Zinc finger protein 335 (NRC-interacting factor 1) (NIF-1)
length: 1342
go: ENSG00000198026;
snps: rs6130982 rs6094231 rs6032606 rs16990961 rs397514642
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:12215545}.
sequence:

opentargets:
histone methyltransferase complex [GO:0035097]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; transcription regulatory region DNA binding [GO:0044212]; brain development [GO:0007420]; brain morphogenesis [GO:0048854]; cerebral cortex neuron differentiation [GO:0021895]; histone H3-K4 trimethylation [GO:0080182]; in utero embryonic development [GO:0001701]; neuron projection morphogenesis [GO:0048812]; positive regulation of lymphocyte proliferation [GO:0050671]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neurogenesis [GO:0050769]; regulation of gene expression [GO:0010468]; regulation of gene expression, epigenetic [GO:0040029]; regulation of histone H3-K4 methylation [GO:0051569]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9H4Z2-1; Sequence=Displayed; Name=2; IsoId=Q9H4Z2-2; Sequence=VSP_035791, VSP_035792; Note=No experimental confirmation available.; 


uniprotID: Q96IR2
geneSymbol: ZNF845
name: Zinc finger protein 845
length: 970
go: ENSG00000213799;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
sequence:


uniprotID: Q8IUH5
geneSymbol: ZDHHC17
pdb: 3EU9;5W7I;5W7J;
length: 632
go: ENSG00000186908;
snps: rs33996476
name:
Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17) (DHHC-17)

sequence:

opentargets:
aggresome [GO:0016235]; cell junction [GO:0030054]; cytoplasmic vesicle membrane [GO:0030659]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi-associated vesicle membrane [GO:0030660]; integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; presynaptic membrane [GO:0042734]; identical protein binding [GO:0042802]; magnesium ion transmembrane transporter activity [GO:0015095]; palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; lipoprotein transport [GO:0042953]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein palmitoylation [GO:0018345]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q8IUH5-1; Sequence=Displayed; Name=2; IsoId=Q8IUH5-2; Sequence=VSP_010021, VSP_010022, VSP_010024, VSP_010025; Name=3; IsoId=Q8IUH5-3; Sequence=VSP_010023; Note=No experimental confirmation available.; 

location:
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000269|PubMed:15603740, ECO:0000269|PubMed:18794299}; Multi-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:18794299}; Multi-pass membrane protein {ECO:0000255}. Cell junction, synapse, presynaptic cell membrane {ECO:0000269|PubMed:18032660}; Multi-pass membrane protein {ECO:0000255}. Note=Low extracellular Mg(2+) induces increase in Golgi and in post-Golgi membrane vesicles. {ECO:0000269|PubMed:18794299}.


uniprotID: O76080
geneSymbol: ZFAND5
length: 213
go: ENSG00000107372;
location: SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
name:
AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216)

sequence:

opentargets:
cytoplasm [GO:0005737]; DNA binding [GO:0003677]; zinc ion binding [GO:0008270]; face development [GO:0060324]; fibroblast migration [GO:0010761]; in utero embryonic development [GO:0001701]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; respiratory system process [GO:0003016]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculature development [GO:0001944]


uniprotID: Q9NYG2
geneSymbol: ZDHHC3
length: 299
go: ENSG00000163812;
name:
Palmitoyltransferase ZDHHC3 (EC 2.3.1.225) (Protein DHHC1) (Zinc finger DHHC domain-containing protein 3) (DHHC-3)

sequence:

opentargets:
endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; localization within membrane [GO:0051668]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein localization to photoreceptor outer segment [GO:1903546]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9NYG2-1; Sequence=Displayed; Name=2; IsoId=Q9NYG2-2; Sequence=VSP_006934; 

location:
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000269|PubMed:21926431}; Multi-pass membrane protein {ECO:0000255}.


uniprotID: A8MWA4
geneSymbol: ZNF705E
reactome: R-HSA-212436;
name: Putative zinc finger protein 705E
length: 300
go: ENSG00000214534;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: A8MVS1
geneSymbol: ZNF705F
reactome: R-HSA-212436;
name: Zinc finger protein 705F
length: 300
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
sequence:


uniprotID: O60765
geneSymbol: ZNF354A
reactome: R-HSA-212436;
name: Zinc finger protein 354A (Transcription factor 17) (TCF-17) (Zinc finger protein eZNF)
length: 605
go: ENSG00000169131;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:23665872}.
sequence:

opentargets:
cytosol [GO:0005829]; nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; regulation of transcription by RNA polymerase II [GO:0006357]; sensory perception of sound [GO:0007605]


uniprotID: P52738
geneSymbol: ZNF140
reactome: R-HSA-212436;
name: Zinc finger protein 140
length: 457
go: ENSG00000196387;
snps: rs2229373
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; negative regulation of transcription by RNA polymerase II [GO:0000122]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=P52738-1; Sequence=Displayed; Name=2; IsoId=P52738-2; Sequence=VSP_056436; 


uniprotID: O15090
geneSymbol: ZNF536
name: Zinc finger protein 536
length: 1300
go: ENSG00000198597;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001078]; retinoic acid-responsive element binding [GO:0044323]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription by RNA polymerase II [GO:0000122]


uniprotID: Q9UDW3
geneSymbol: ZMAT5
reactome: R-HSA-72165;
length: 170
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15146077}.
name:
Zinc finger matrin-type protein 5 (U11/U12 small nuclear ribonucleoprotein 20 kDa protein) (U11/U12 snRNP 20 kDa protein) (U11/U12-20K)

sequence:
MGKRYFCDYCDRSFQDNLHNRKKHLNGLQHLKAKKVWYDMFRDAAAILLDEQNKRPCRKFLLTGQCDFGSNCRFSHMSERDLQELSIQVEEERRAREWLLDAPELPEGHLEDWLEKRAKRLSSAPSSRAEPIRTTVFQYPVGWPPVQELPPSLRAPPPGGWPLQPRVQWG

opentargets:
nucleoplasm [GO:0005654]; U12-type spliceosomal complex [GO:0005689]; zinc ion binding [GO:0008270]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]


uniprotID: P52743
geneSymbol: ZNF137P
name: Putative zinc finger protein 137 (Zinc finger protein 137 pseudogene)
length: 207
snps: rs7250969 rs1802617
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; metal ion binding [GO:0046872]


uniprotID: Q14585
geneSymbol: ZNF345
name: Zinc finger protein 345 (Zinc finger protein HZF10)
length: 488
go: ENSG00000251247;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of transcription by RNA polymerase III [GO:0006359]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383]


uniprotID: B4DU55
geneSymbol: ZNF879
name: Zinc finger protein 879
length: 563
go: ENSG00000234284;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q6ZR03
name: Uncharacterized protein FLJ46757
length: 302
sequence:


uniprotID: Q96C55
geneSymbol: ZNF524
name: Zinc finger protein 524
length: 264
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q6ZMS4
geneSymbol: ZNF852
name: Zinc finger protein 852
length: 543
go: ENSG00000178917;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
sequence:


uniprotID: O43167
geneSymbol: ZBTB24
name: Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450)
length: 697
go: ENSG00000112365;
snps: rs387907105 rs2232448
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleoplasm [GO:0005654]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; transcription regulatory region DNA binding [GO:0044212]; hematopoietic progenitor cell differentiation [GO:0002244]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=O43167-1; Sequence=Displayed; Name=2; IsoId=O43167-2; Sequence=VSP_016221, VSP_016222; Note=No experimental confirmation available.; 


uniprotID: Q96SZ4
geneSymbol: ZSCAN10
reactome: R-HSA-452723;
name: Zinc finger and SCAN domain-containing protein 10 (Zinc finger protein 206)
length: 725
go: ENSG00000130182;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}.
sequence:

opentargets:
nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; sequence-specific DNA binding [GO:0043565]; negative regulation of transcription, DNA-templated [GO:0045892]; somatic stem cell population maintenance [GO:0035019]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q96SZ4-1; Sequence=Displayed; Name=2; IsoId=Q96SZ4-2; Sequence=VSP_039221; Note=No experimental confirmation available.; Name=3; IsoId=Q96SZ4-3; Sequence=VSP_054601, VSP_054602; Note=No experimental confirmation available.; 


uniprotID: Q9BSK1
geneSymbol: ZNF577
reactome: R-HSA-212436;
name: Zinc finger protein 577
length: 485
go: ENSG00000161551;
snps: rs17856123 rs17849895 rs9807847 rs2288868 rs9807842 rs9807853 rs10407547 rs10407911
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9BSK1-1; Sequence=Displayed; Name=2; IsoId=Q9BSK1-2; Sequence=VSP_040810; 


uniprotID: O75132
geneSymbol: ZBED4
name: Zinc finger BED domain-containing protein 4
length: 1171
go: ENSG00000100426;
snps: rs910799
location: SUBCELLULAR LOCATION: Nucleus. Cytoplasm.
sequence:

opentargets:
cytoplasm [GO:0005737]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein dimerization activity [GO:0046983]


uniprotID: Q9HCZ1
geneSymbol: ZNF334
reactome: R-HSA-212436;
name: Zinc finger protein 334
length: 680
go: ENSG00000198185;
snps: rs3764690
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: P17030
geneSymbol: ZNF25
reactome: R-HSA-212436;
name: Zinc finger protein 25 (Zinc finger protein KOX19)
length: 456
go: ENSG00000175395;
snps: rs1208606
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=P17030-1; Sequence=Displayed; Name=2; IsoId=P17030-2; Sequence=VSP_007846, VSP_007847; Note=No experimental confirmation available.; 


uniprotID: Q8N9Z0
geneSymbol: ZNF610
reactome: R-HSA-212436;
name: Zinc finger protein 610
length: 462
go: ENSG00000167554;
snps: rs3815905 rs2241586 rs321937 rs7343101
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q8N9Z0-1; Sequence=Displayed; Name=2; IsoId=Q8N9Z0-2; Sequence=VSP_018387; Note=No experimental confirmation available.; 


uniprotID: Q6PJT7
geneSymbol: ZC3H14
length: 736
go: ENSG00000100722;
name:
Zinc finger CCCH domain-containing protein 14 (Mammalian suppressor of tau pathology-2) (MSUT-2) (Renal carcinoma antigen NY-REN-37)

sequence:

opentargets:
axon cytoplasm [GO:1904115]; cytoplasm [GO:0005737]; dendrite cytoplasm [GO:0032839]; nuclear speck [GO:0016607]; nucleolus [GO:0005730]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904]; metal ion binding [GO:0046872]; poly(A) binding [GO:0008143]; RNA binding [GO:0003723]; negative regulation of mRNA polyadenylation [GO:1900364]; regulation of mRNA stability [GO:0043488]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=10;  Name=1; Synonyms=Isoform 1; IsoId=Q6PJT7-1; Sequence=Displayed; Name=2; IsoId=Q6PJT7-2; Sequence=VSP_033171; Name=3; Synonyms=Isoform 2; IsoId=Q6PJT7-3; Sequence=VSP_033166, VSP_033171; Name=4; Synonyms=Isoform 3 short; IsoId=Q6PJT7-4; Sequence=VSP_033164, VSP_033168; Name=5; IsoId=Q6PJT7-5; Sequence=VSP_033167; Name=6; Synonyms=Isoform 4; IsoId=Q6PJT7-6; Sequence=VSP_033163, VSP_033165, VSP_033168, VSP_033171; Name=8; IsoId=Q6PJT7-8; Sequence=VSP_033162, VSP_033169; Name=9; IsoId=Q6PJT7-9; Sequence=VSP_044645, VSP_033171; Note=No experimental confirmation available.; Name=10; IsoId=Q6PJT7-10; Sequence=VSP_055097, VSP_033166; Note=No experimental confirmation available.; Name=11; IsoId=Q6PJT7-11; Sequence=VSP_055096, VSP_033168, VSP_033171; Note=No experimental confirmation available.; 

location:
SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000269|PubMed:17630287, ECO:0000269|PubMed:19303045, ECO:0000269|PubMed:24671764}. Note=Colocalizes with poly(A) RNA in nuclear speckles. {ECO:0000250|UniProtKB:Q7TMD5}.; SUBCELLULAR LOCATION: Isoform 1: Nucleus speckle.; SUBCELLULAR LOCATION: Isoform 3: Nucleus speckle.; SUBCELLULAR LOCATION: Isoform 6: Cytoplasm {ECO:0000269|PubMed:21734151}.


uniprotID: Q5T7W0
geneSymbol: ZNF618
name: Zinc finger protein 618
length: 954
go: ENSG00000157657;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=4;  Name=1; IsoId=Q5T7W0-1; Sequence=Displayed; Name=2; IsoId=Q5T7W0-2; Sequence=VSP_025179, VSP_025180, VSP_025181; Note=No experimental confirmation available.; Name=3; IsoId=Q5T7W0-3; Sequence=VSP_025179, VSP_025182, VSP_025183; Note=No experimental confirmation available.; Name=4; IsoId=Q5T7W0-4; Sequence=VSP_025179, VSP_055968; Note=No experimental confirmation available.; 


uniprotID: Q8N0V1
geneSymbol: ZNF295-AS1
length: 137
name:
Putative uncharacterized protein ZNF295-AS1 (ZNF295 antisense RNA 1) (ZNF295 antisense gene protein 1)

sequence:
MKDKMWCEDTAQPHRRLPAPPSSSSPTVVFQSHRRLLAPPSSSWTLWVAPRCGCCSPLCPKRVCASLCRVLAVTWSLTKLPFPLSPILLSRPGWLPQPSSPGPACAEPSSQEGGDTDLRSYGCFVCGWAWPTLSPRP


uniprotID: Q8N680
geneSymbol: ZBTB2
name: Zinc finger and BTB domain-containing protein 2
length: 514
go: ENSG00000181472;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001078]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; negative regulation of transcription by RNA polymerase II [GO:0000122]


uniprotID: Q9NRM2
geneSymbol: ZNF277
name: Zinc finger protein 277 (Nuclear receptor-interacting factor 4)
length: 450
go: ENSG00000198839;
snps: rs34571830 rs11539696
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; cellular response to hydrogen peroxide [GO:0070301]; regulation of cellular senescence [GO:2000772]


uniprotID: Q9Y493
geneSymbol: ZAN
name: Zonadhesin
length: 2812
go: ENSG00000146839;
sequence:

opentargets:
integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; binding of sperm to zona pellucida [GO:0007339]; cell-cell adhesion [GO:0098609]

snps:
rs12673246 rs34828430 rs17162408 rs221833 rs13241461 rs6942733 rs221823 rs2293767 rs10953303 rs10247980 rs17147735 rs314298 rs12673041 rs314299 rs542137 rs541275 rs539445 rs314300 rs531503 rs60783739 rs59541653 rs3847059 rs314339 

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=7;  Name=3; IsoId=Q9Y493-1; Sequence=Displayed; Name=1; IsoId=Q9Y493-2; Sequence=VSP_001430, VSP_001431; Note=May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.; Name=2; IsoId=Q9Y493-3; Sequence=VSP_001428, VSP_001429; Note=May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.; Name=4; IsoId=Q9Y493-4; Sequence=VSP_001424, VSP_001425; Note=May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.; Name=5; IsoId=Q9Y493-5; Sequence=VSP_001420, VSP_001421; Note=May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.; Name=6; IsoId=Q9Y493-6; Sequence=VSP_001422, VSP_001423; Name=7; IsoId=Q9Y493-7; Sequence=VSP_001426, VSP_001427; 

location:
SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Note=Exclusively on the apical region of the sperm head. {ECO:0000250}.


uniprotID: Q9UFV3
name: Putative uncharacterized protein DKFZp434L187
length: 132
sequence:
MAETYRRSRQHEQLPGQRHMDLLTGYSKLIQSRLKLLLHLGSQPPVGKTFFFSCWCHPLFHGSKTTPNVWYKFSETALSILNSCQASQLGVRKMPGDMSSSPRVREFSALVAIKEKIHILPTNAKVGSKFGS


uniprotID: Q86U90
geneSymbol: YRDC
length: 279
go: ENSG00000196449;
name:
YrdC domain-containing protein, mitochondrial (Dopamine receptor-interacting protein 3) (Ischemia/reperfusion-inducible protein homolog) (hIRIP)

sequence:

opentargets:
cytoplasm [GO:0005737]; membrane [GO:0016020]; mitochondrion [GO:0005739]; double-stranded RNA binding [GO:0003725]; nucleotidyltransferase activity [GO:0016779]; tRNA binding [GO:0000049]; negative regulation of transport [GO:0051051]; regulation of translational fidelity [GO:0006450]

location:
SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}. Membrane; Peripheral membrane protein. Note=Predominantly localized in the plasma membrane. {ECO:0000250}.


uniprotID: Q6ZST2
geneSymbol: ZCCHC23
name: Zinc finger CCHC domain-containing protein 23
length: 131
opentargets: nucleic acid binding [GO:0003676]; zinc ion binding [GO:0008270]
sequence:
MLLLNQTLATTEKQTALQAAEKFVDELCISYSAKKGRGYARKRQKNLLATLQAYKPQNPKDAPVNCDKCGKPGNVKNDCPGSMRKPARPCPICGGDHWRVDCPQRCRSLGPKPVSQVSNRIDGPQGSCPWL


uniprotID: Q9H521
name: Putative uncharacterized protein LOC645739
sequence: MVWQENEDLRKQLVEASELLKSQAKELKDAHQQQKLALQDFLELCELVAELCSQKQKVWDKEGEMEVAMQKVNTMWQES
length: 79
opentargets:
protein serine/threonine kinase activity [GO:0004674]; actin cytoskeleton organization [GO:0030036]; cell migration [GO:0016477]


uniprotID: A8MXK9
name: Uncharacterized protein ENSP00000382033
length: 166
sequence:
MLCPCIQESTFETCLFMAVSRMSKWRLSRVGGSRSLPAEMEVLGEVWCVRAEEQPMTGLGIVWHSPLDKALETWSLQQQPDFSLGLGHLGLGTDATWMQSFPGSGGDAQAGTGVSGPLRLYPNLLCDFGPRQGPLWALLLEKRQMAGTGGSPALLAWRSASWRALG

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=A8MXK9-1; Sequence=Displayed; Name=2; IsoId=A8MXK9-2; Sequence=VSP_033356; 


uniprotID: Q8N9W7
name: Putative transmembrane protein FLJ36131
length: 124
opentargets: integral component of membrane [GO:0016021]
location: SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
sequence:
MYVSISFLLGLSHLVLCCLLTFIVNFYLPPESIDFEFMAHNWSKGRSPSSTLGLSWFKAGFRFSDGWSMFYSFGLPGVALPGSPPRSHLLPGTQILIRSFQPCESAKHSARLSSLLTTTSYSVS


uniprotID: Q6ZVL8
name: Putative uncharacterized protein FLJ42384
length: 140
snps: rs8060538 rs8055082 rs9940490 rs8053661 rs8055382
sequence:
MWPFRLRCPIYFKTRLLYSSSQDGFLSSSTNYYNHRTYPGLVNWLFVLTEPELTGELGDDDRKGMHTGGIIRWLGRPSSQLKPIFHAEERRVPPPPERLVGRASPREQATVFKRICAPLHAEVFCRAGLCACHPDCTAAG


uniprotID: Q6ZS49
name: Putative uncharacterized protein FLJ45831
length: 121
opentargets: extracellular space [GO:0005615]
sequence:
MEISCTSQGFFFLKEHSSGVSSVKAAQMPGRTLYRSLCSCVFPLHSPTRPPSPASAPKGFLLLSPTSSNASKLMPYYLFHRSRGVDNSKISVLILLGCELEQTKKKKLGPATALGNSGRVE


uniprotID: Q6ZSR6
name: Putative uncharacterized protein FLJ45256
length: 202
sequence:


uniprotID: Q9Y3S2
geneSymbol: ZNF330
name: Zinc finger protein 330 (Nucleolar autoantigen 36) (Nucleolar cysteine-rich protein)
length: 320
go: ENSG00000109445;
snps: rs35353789 rs34631212
sequence:

opentargets:
chromosome, centromeric region [GO:0000775]; midbody [GO:0030496]; nucleolus [GO:0005730]; metal ion binding [GO:0046872]; zinc ion binding [GO:0008270]

location:
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10593942}. Nucleus, nucleolus {ECO:0000269|PubMed:10593942}. Chromosome, centromere {ECO:0000269|PubMed:10593942}. Note=Predominantly expressed in the nucleolus. In mitosis associated with centromeres and concentrated at the midbody in cytokinesis.


uniprotID: A8MX80
name: Putative UPF0607 protein ENSP00000383144
length: 341
sequence:


uniprotID: Q9UF83
name: Uncharacterized protein DKFZp434B061
length: 564
opentargets: extracellular space [GO:0005615]
sequence:


uniprotID: Q6ZRX8
name: Putative uncharacterized protein FLJ45999
length: 168
sequence:
MSPTTGPQPNPRAWECHHTTGPQPNPRAWECHRMKGPQPNPRAWECHLRRVHNLTPEPGNVTIRGVHILTPEPGNVTIRGVHNLTPEPGNVTERGVHNLTPEPGNVTERGVHNLIPEPGNVTVKRGPQPNPRAWECHRTRGPQPNPRAWECHRTRGPQPNPRAWECHR


uniprotID: O15231
geneSymbol: ZNF185
name: Zinc finger protein 185 (LIM domain protein ZNF185) (P1-A)
length: 689
go: ENSG00000147394;
sequence:

opentargets:
actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; focal adhesion [GO:0005925]; actin filament binding [GO:0051015]; zinc ion binding [GO:0008270]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=9;  Name=1; IsoId=O15231-1; Sequence=Displayed; Name=2; IsoId=O15231-2; Sequence=VSP_039898, VSP_039899, VSP_039900, VSP_039901, VSP_039902; Note=No experimental confirmation available. {ECO:0000244|PubMed:23186163}; Name=3; IsoId=O15231-3; Sequence=VSP_039900; Name=4; IsoId=O15231-4; Sequence=VSP_043405; Name=5; IsoId=O15231-5; Sequence=VSP_045080, VSP_045081, VSP_043405; Note=No experimental confirmation available.; Name=6; IsoId=O15231-6; Sequence=VSP_047206; Name=7; IsoId=O15231-7; Sequence=VSP_047205; Name=8; IsoId=O15231-8; Sequence=VSP_047205, VSP_047206; Name=9; IsoId=O15231-9; Sequence=VSP_054773; Note=No experimental confirmation available.; 

location:
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:16799630}. Cell junction, focal adhesion {ECO:0000269|PubMed:16799630}.


uniprotID: Q9ULD9
geneSymbol: ZNF608
name: Zinc finger protein 608 (Renal carcinoma antigen NY-REN-36)
length: 1512
go: ENSG00000168916;
snps: rs6862252
sequence:

opentargets:
metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; negative regulation of transcription by RNA polymerase II [GO:0000122]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9ULD9-1; Sequence=Displayed; Name=2; IsoId=Q9ULD9-2; Sequence=VSP_023664; Note=No experimental confirmation available.; 


uniprotID: Q9C0G0
geneSymbol: ZNF407
name: Zinc finger protein 407
length: 2248
go: ENSG00000215421;
snps: rs3794942 rs7227263 rs948615 rs34048449 rs17056248
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; zinc ion binding [GO:0008270]; regulation of gene expression [GO:0010468]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q9C0G0-1; Sequence=Displayed; Name=2; IsoId=Q9C0G0-2; Sequence=VSP_028845, VSP_028846; Note=No experimental confirmation available.; Name=3; IsoId=Q9C0G0-3; Sequence=VSP_028843, VSP_028844; Note=No experimental confirmation available.; 


uniprotID: Q6ZN19
geneSymbol: ZNF841
name: Zinc finger protein 841
length: 808
go: ENSG00000197608;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q6ZN19-1; Sequence=Displayed; Name=2; IsoId=Q6ZN19-2; Sequence=VSP_033755; Note=No experimental confirmation available.; Name=3; IsoId=Q6ZN19-3; Sequence=VSP_040752; 


uniprotID: P37275
geneSymbol: ZEB1
reactome: R-HSA-6785807;
pdb: 2E19;
length: 1124
go: ENSG00000148516;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:20418909, ECO:0000269|PubMed:25190660}.
name:
Zinc finger E-box-binding homeobox 1 (NIL-2-A zinc finger protein) (Negative regulator of IL2) (Transcription factor 8) (TCF-8)

sequence:

opentargets:
cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription factor complex [GO:0005667]; chromatin binding [GO:0003682]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; E-box binding [GO:0070888]; transcription coactivator activity [GO:0003713]; transcription corepressor activity [GO:0003714]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; cartilage development [GO:0051216]; cell proliferation [GO:0008283]; cellular response to amino acid stimulus [GO:0071230]; central nervous system development [GO:0007417]; cochlea morphogenesis [GO:0090103]; cytokine-mediated signaling pathway [GO:0019221]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic skeletal system morphogenesis [GO:0048704]; immune response [GO:0006955]; negative regulation of cell proliferation [GO:0008285]; negative regulation of endothelial cell differentiation [GO:0045602]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; pattern specification process [GO:0007389]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of mesenchymal cell proliferation [GO:0010464]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; semicircular canal morphogenesis [GO:0048752]

snps:
rs80194531 rs12217419 rs35753967 rs779148597 rs781750314 rs567252241 rs199944415 rs118020901 rs78449005 

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=5;  Name=1; IsoId=P37275-1; Sequence=Displayed; Name=2; IsoId=P37275-2; Sequence=VSP_045184; Note=No experimental confirmation available.; Name=3; IsoId=P37275-3; Sequence=VSP_047280; Name=4; IsoId=P37275-4; Sequence=VSP_047281; Name=5; IsoId=P37275-5; Sequence=VSP_047279, VSP_045184; 


uniprotID: Q9HBF4
geneSymbol: ZFYVE1
length: 777
go: ENSG00000165861;
name:
Zinc finger FYVE domain-containing protein 1 (Double FYVE-containing protein 1) (SR3) (Tandem FYVE fingers-1)

sequence:

opentargets:
autophagosome [GO:0005776]; endoplasmic reticulum [GO:0005783]; extrinsic component of omegasome membrane [GO:0097629]; Golgi stack [GO:0005795]; Mitochondria-associated ER Membrane [GO:0044233]; omegasome [GO:1990462]; perinuclear region of cytoplasm [GO:0048471]; phagophore assembly site [GO:0000407]; 1-phosphatidylinositol binding [GO:0005545]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; zinc ion binding [GO:0008270]; cellular response to starvation [GO:0009267]; macroautophagy [GO:0016236]; negative regulation of phosphatase activity [GO:0010923]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q9HBF4-1; Sequence=Displayed; Name=2; IsoId=Q9HBF4-2; Sequence=VSP_008007; Name=3; IsoId=Q9HBF4-3; Sequence=VSP_056770; 

location:
SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack. Endoplasmic reticulum. Note=Resides predominantly in the cisternal stacks of the Golgi. Colocalizes with TRIM13 on the perinuclear endoplasmic reticulum.


uniprotID: A8MXY4
geneSymbol: ZNF99
reactome: R-HSA-212436;
name: Zinc finger protein 99
length: 864
go: ENSG00000213973;
snps: rs34726149 rs7255780
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q9BR11
geneSymbol: ZSWIM1
name: Zinc finger SWIM domain-containing protein 1
length: 485
go: ENSG00000168612;
opentargets: nucleus [GO:0005634]; zinc ion binding [GO:0008270]
snps: rs3746500
sequence:


uniprotID: Q8NF64
geneSymbol: ZMIZ2
name: Zinc finger MIZ domain-containing protein 2 (PIAS-like protein Zimp7)
length: 920
go: ENSG00000122515;
snps: rs3735478
sequence:

opentargets:
mitochondrion [GO:0005739]; nuclear replication fork [GO:0043596]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; nuclear receptor transcription coactivator activity [GO:0030374]; zinc ion binding [GO:0008270]; positive regulation of transcription by RNA polymerase II [GO:0045944]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q8NF64-1; Sequence=Displayed; Name=2; IsoId=Q8NF64-2; Sequence=VSP_012190; Name=3; IsoId=Q8NF64-3; Sequence=VSP_024918, VSP_012190; Note=No experimental confirmation available.; 

location:
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16051670, ECO:0000269|PubMed:9853615}. Note=Detected at replication foci throughout S phase.


uniprotID: Q96M66
name: Putative uncharacterized protein FLJ32790
length: 194
snps: rs350229 rs11648228
sequence:
MAAKSTQDSLPRDTGEPSALPVQGRAEGRSSEGRKERTAECALRGKQASEPALRKRNFLPGPNSDTVRPAAETELVPCSLRHPRQDLCGEHPSFPVMQPSLETQAKPERDRAVLIPPKGPWPPAQGLAMRTHCPTGPPSKAYCRGGSSSTSRNQVASLAYRTQNTAASQPRQPGGRGKEDTAGYGSCSPRSLAV


uniprotID: Q8IZN3
geneSymbol: ZDHHC14
length: 488
go: ENSG00000175048;
snps: rs8180688
location: SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
name:
Probable palmitoyltransferase ZDHHC14 (EC 2.3.1.225) (NEW1 domain-containing protein) (NEW1CP) (Zinc finger DHHC domain-containing protein 14) (DHHC-14)

sequence:

opentargets:
endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; integral component of membrane [GO:0016021]; palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q8IZN3-1; Sequence=Displayed; Name=2; IsoId=Q8IZN3-2; Sequence=VSP_008651; 


uniprotID: Q9H4I2
geneSymbol: ZHX3
pdb: 2DA5;2DN0;
length: 956
go: ENSG00000174306;
snps: rs17265513
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:12659632}.
name:
Zinc fingers and homeoboxes protein 3 (Triple homeobox protein 1) (Zinc finger and homeodomain protein 3)

sequence:

opentargets:
nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; transcription corepressor activity [GO:0003714]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of osteoblast differentiation [GO:0045669]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9H4I2-1; Sequence=Displayed; Name=2; IsoId=Q9H4I2-2; Sequence=VSP_054307; Note=No experimental confirmation available.; 


uniprotID: Q96JL9
geneSymbol: ZNF333
reactome: R-HSA-212436;
name: Zinc finger protein 333
length: 665
go: ENSG00000160961;
snps: rs3885179 rs3764626
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q96JL9-1; Sequence=Displayed; Name=2; IsoId=Q96JL9-2; Sequence=VSP_055945, VSP_055946; Name=3; IsoId=Q96JL9-3; Sequence=VSP_055947, VSP_055948; Note=No experimental confirmation available.; 


uniprotID: Q14593
geneSymbol: ZNF273
reactome: R-HSA-212436;
name: Zinc finger protein 273 (Zinc finger protein HZF9)
length: 569
go: ENSG00000198039;
snps: rs1830080 rs2017252
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q14593-1; Sequence=Displayed; Note=No experimental confirmation available. Derived from EST data.; Name=2; IsoId=Q14593-2; Sequence=VSP_038180; 


uniprotID: A6NDX5
geneSymbol: ZNF840P
reactome: R-HSA-212436;
name: Putative zinc finger protein 840 (Zinc finger protein 840 pseudogene)
length: 716
snps: rs3752261
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
sequence:


uniprotID: O75312
geneSymbol: ZPR1
name: Zinc finger protein ZPR1 (Zinc finger protein 259)
length: 459
go: ENSG00000109917;
snps: rs35120633
sequence:

opentargets:
axon [GO:0030424]; Cajal body [GO:0015030]; cytoplasm [GO:0005737]; Gemini of coiled bodies [GO:0097504]; growth cone [GO:0030426]; neuronal cell body [GO:0043025]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; SMN complex [GO:0032797]; receptor tyrosine kinase binding [GO:0030971]; translation initiation factor binding [GO:0031369]; zinc ion binding [GO:0008270]; apoptotic process involved in development [GO:1902742]; axon development [GO:0061564]; Cajal body organization [GO:0030576]; cell proliferation [GO:0008283]; cellular response to epidermal growth factor stimulus [GO:0071364]; DNA endoreduplication [GO:0042023]; inner cell mass cell proliferation [GO:0001833]; microtubule cytoskeleton organization [GO:0000226]; mRNA processing [GO:0006397]; negative regulation of motor neuron apoptotic process [GO:2000672]; positive regulation of gene expression [GO:0010628]; positive regulation of growth [GO:0045927]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of RNA splicing [GO:0033120]; positive regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0071931]; pre-mRNA catabolic process [GO:1990261]; regulation of myelination [GO:0031641]; RNA splicing [GO:0008380]; signal transduction [GO:0007165]; spinal cord development [GO:0021510]; trophectodermal cell proliferation [GO:0001834]

location:
SUBCELLULAR LOCATION: Nucleus. Nucleus, nucleolus. Nucleus, gem. Nucleus, Cajal body. Cytoplasm, perinuclear region. Cytoplasm. Cell projection, axon {ECO:0000250}. Cell projection, growth cone {ECO:0000250}. Note=Colocalized with SMN1 in Gemini of coiled bodies (gems), Cajal bodies, axon and growth cones of neurons (By similarity). Localized predominantly in the cytoplasm in serum-starved cells growth arrested in G0 of the mitotic cell cycle. Localized both in the nucleus and cytoplasm at the G1 phase of the mitotic cell cycle. Accumulates in the subnuclear bodies during progression into the S phase of the mitotic cell cycle. Diffusely localized throughout the cell during mitosis. Colocalized with NPAT and SMN1 in nuclear bodies including gems (Gemini of coiled bodies) and Cajal bodies in a cell cycle-dependent manner. Translocates together with EEF1A1 from the cytoplasm to the nucleolus after treatment with mitogens. Colocalized with EGFR in the cytoplasm of quiescent cells. Translocates from the cytoplasm to the nucleus in a epidermal growth factor (EGF)-dependent manner. {ECO:0000250}.


uniprotID: E7ETH6
geneSymbol: ZNF587B
name: Zinc finger protein 587B
length: 402
go: ENSG00000269343;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q96DA0
geneSymbol: ZG16B
pdb: 3AQG;
name: Zymogen granule protein 16 homolog B
length: 208
go: ENSG00000162078;
snps: rs35533993
location: SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
sequence:

opentargets:
extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; carbohydrate binding [GO:0030246]; retina homeostasis [GO:0001895]


uniprotID: Q96MV8
geneSymbol: ZDHHC15
length: 337
go: ENSG00000102383;
name:
Palmitoyltransferase ZDHHC15 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 15) (DHHC-15)

sequence:

opentargets:
endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; metal ion binding [GO:0046872]; palmitoyltransferase activity [GO:0016409]; protein-cysteine S-palmitoyltransferase activity [GO:0019706]; peptidyl-L-cysteine S-palmitoylation [GO:0018230]; protein palmitoylation [GO:0018345]; protein targeting to membrane [GO:0006612]; synaptic vesicle maturation [GO:0016188]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q96MV8-1; Sequence=Displayed; Name=2; IsoId=Q96MV8-2; Sequence=VSP_013206, VSP_013207, VSP_013208; Note=No experimental confirmation available.; Name=3; IsoId=Q96MV8-3; Sequence=VSP_013206; Note=No experimental confirmation available.; 

location:
SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250|UniProtKB:F1QXD3}; Multi-pass membrane protein {ECO:0000250|UniProtKB:F1QXD3}.


uniprotID: Q9H898
geneSymbol: ZMAT4
name: Zinc finger matrin-type protein 4
length: 229
go: ENSG00000165061;
opentargets: nucleus [GO:0005634]; DNA binding [GO:0003677]; zinc ion binding [GO:0008270]
snps: rs17851751
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9H898-1; Sequence=Displayed; Name=2; IsoId=Q9H898-2; Sequence=VSP_027476; 


uniprotID: Q8N446
geneSymbol: ZNF843
name: Zinc finger protein 843
length: 348
go: ENSG00000176723;
opentargets: metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
sequence:


uniprotID: Q9ULJ3
geneSymbol: ZBTB21
pdb: 1WJP;
name: Zinc finger and BTB domain-containing protein 21 (Zinc finger protein 295)
length: 1066
go: ENSG00000173276;
snps: rs871545 rs871546
sequence:

opentargets:
cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; methyl-CpG binding [GO:0008327]; negative regulation of transcription, DNA-templated [GO:0045892]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; Synonyms=ZNF295L; IsoId=Q9ULJ3-1; Sequence=Displayed; Name=2; Synonyms=ZNF295S; IsoId=Q9ULJ3-2; Sequence=VSP_041349; 

location:
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15629158}. Note=Colocalizes with ZBTB14 in nucleus in HEK293 cells.


uniprotID: Q15915
geneSymbol: ZIC1
name: Zinc finger protein ZIC 1 (Zinc finger protein 201) (Zinc finger protein of the cerebellum 1)
length: 447
go: ENSG00000152977;
snps: rs1057517670 rs143292136
sequence:

opentargets:
cytoplasm [GO:0005737]; nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001077]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; adult walking behavior [GO:0007628]; brain development [GO:0007420]; cell differentiation [GO:0030154]; inner ear morphogenesis [GO:0042472]; pattern specification process [GO:0007389]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of transcription, DNA-templated [GO:0045893]; regulation of smoothened signaling pathway [GO:0008589]; spinal cord development [GO:0021510]

location:
SUBCELLULAR LOCATION: Nucleus. Cytoplasm {ECO:0000250}. Note=Localizes in the cytoplasm in presence of MDFIC overexpression. {ECO:0000250}.


uniprotID: Q8N9F8
geneSymbol: ZNF454
reactome: R-HSA-212436;
name: Zinc finger protein 454
length: 522
go: ENSG00000178187;
snps: rs6867221 rs12719860
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: P17031
geneSymbol: ZNF26
reactome: R-HSA-212436;
name: Zinc finger protein 26 (Zinc finger protein KOX20)
length: 533
go: ENSG00000198393;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q52M93
geneSymbol: ZNF585B
reactome: R-HSA-212436;
name: Zinc finger protein 585B (zinc finger protein 41-like protein)
length: 769
go: ENSG00000245680;
snps: rs1657509
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q96BR9
geneSymbol: ZBTB8A
length: 441
opentargets: nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]
snps: rs704886
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
name:
Zinc finger and BTB domain-containing protein 8A (BTB/POZ and zinc-finger domain-containing factor) (BTB/POZ and zinc-finger domains factor on chromosome 1) (BOZ-F1)

sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q96BR9-1; Sequence=Displayed; Name=2; IsoId=Q96BR9-2; Sequence=VSP_037597; 


uniprotID: Q9NUD5
geneSymbol: ZCCHC3
name: Zinc finger CCHC domain-containing protein 3
length: 403
opentargets: RNA binding [GO:0003723]; zinc ion binding [GO:0008270]
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9NUD5-1; Sequence=Displayed; Name=2; IsoId=Q9NUD5-2; Sequence=VSP_055996; Note=No experimental confirmation available.; 


uniprotID: Q6ZN79
geneSymbol: ZNF705A
reactome: R-HSA-212436;
name: Zinc finger protein 705A
length: 300
go: ENSG00000196946;
snps: rs10743251 rs10743252 rs10743253 rs11043758
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: O14628
geneSymbol: ZNF195
reactome: R-HSA-212436;
name: Zinc finger protein 195
length: 629
go: ENSG00000005801;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; zinc ion binding [GO:0008270]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=8;  Name=1; Synonyms=A; IsoId=O14628-1; Sequence=Displayed; Name=2; Synonyms=B; IsoId=O14628-2; Sequence=Not described; Name=3; Synonyms=C; IsoId=O14628-3; Sequence=Not described; Name=4; IsoId=O14628-4; Sequence=VSP_036880; Name=5; IsoId=O14628-5; Sequence=VSP_036881; Name=6; IsoId=O14628-6; Sequence=VSP_036879, VSP_036881; Name=7; IsoId=O14628-7; Sequence=VSP_036879, VSP_036880; Name=8; IsoId=O14628-8; Sequence=VSP_036879, VSP_045071, VSP_045072; Note=No experimental confirmation available.; 


uniprotID: Q49A33
geneSymbol: ZNF876P
name: Putative zinc finger protein 876
length: 203
opentargets: nucleus [GO:0005634]; DNA binding [GO:0003677]; metal ion binding [GO:0046872]
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:


uniprotID: Q147U1
geneSymbol: ZNF846
name: Zinc finger protein 846
length: 533
go: ENSG00000196605;
snps: rs10414485 rs10420364
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q147U1-1; Sequence=Displayed; Name=2; IsoId=Q147U1-3; Sequence=VSP_033362, VSP_033363; Note=No experimental confirmation available.; 


uniprotID: Q8N5A5
geneSymbol: ZGPAT
pdb: 4II1;
length: 531
go: ENSG00000197114;
snps: rs1291212
name:
Zinc finger CCCH-type with G patch domain-containing protein (G patch domain-containing protein 6) (Zinc finger CCCH domain-containing protein 9) (Zinc finger and G patch domain-containing protein)

sequence:

opentargets:
nucleus [GO:0005634]; plasma membrane [GO:0005886]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001078]; RNA polymerase II proximal promoter sequence-specific DNA binding [GO:0000978]; sequence-specific DNA binding [GO:0043565]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription, DNA-templated [GO:0045892]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=4;  Name=1; IsoId=Q8N5A5-1; Sequence=Displayed; Note=No experimental confirmation available.; Name=2; IsoId=Q8N5A5-2; Sequence=VSP_007754; Name=3; IsoId=Q8N5A5-3; Sequence=VSP_038121; Note=No experimental confirmation available.; Name=4; Synonyms=sZIP; IsoId=Q8N5A5-4; Sequence=VSP_053599; 

location:
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:19644445}.; SUBCELLULAR LOCATION: Isoform 4: Nucleus {ECO:0000269|PubMed:20233718}.


uniprotID: O95409
geneSymbol: ZIC2
name: Zinc finger protein ZIC 2 (Zinc finger protein of the cerebellum 2)
length: 532
go: ENSG00000043355;
snps: rs794729641
sequence:

opentargets:
cytoplasm [GO:0005737]; nuclear body [GO:0016604]; nucleus [GO:0005634]; chromatin DNA binding [GO:0031490]; DNA binding [GO:0003677]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001077]; RNA polymerase II regulatory region sequence-specific DNA binding [GO:0000977]; brain development [GO:0007420]; cell differentiation [GO:0030154]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription, DNA-templated [GO:0045893]; visual perception [GO:0007601]

location:
SUBCELLULAR LOCATION: Nucleus. Cytoplasm {ECO:0000250}. Note=Localizes in the cytoplasm in presence of MDFIC overexpression. Both phosphorylated and unphosphorylated forms are localized in the nucleus (By similarity). {ECO:0000250}.


uniprotID: Q7Z3I7
geneSymbol: ZNF572
name: Zinc finger protein 572
length: 529
go: ENSG00000180938;
snps: rs10104558 rs10105106 rs10107774 rs7825375
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific [GO:0001077]


uniprotID: Q6ZN55
geneSymbol: ZNF574
name: Zinc finger protein 574
length: 896
go: ENSG00000105732;
snps: rs3745226 rs35898322 rs3745228
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q6ZN55-1; Sequence=Displayed; Name=2; IsoId=Q6ZN55-2; Sequence=VSP_022878; Note=No experimental confirmation available.; 


uniprotID: Q9UJU3
geneSymbol: ZNF112
reactome: R-HSA-212436;
name: Zinc finger protein 112 (Zfp-112) (Zinc finger protein 228)
length: 913
go: ENSG00000062370;
snps: rs11673395 rs4280359 rs16978965 rs10419604 rs2722723 rs2722722 rs2609881
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9UJU3-1; Sequence=Displayed; Name=2; IsoId=Q9UJU3-2; Sequence=VSP_039929; 


uniprotID: Q5JPB2
geneSymbol: ZNF831
name: Zinc finger protein 831
length: 1677
go: ENSG00000124203;
opentargets: metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
snps: rs181984 rs259956 rs201549554
sequence:


uniprotID: Q6ZTB9
geneSymbol: ZNF833P
name: Putative zinc finger protein 833
length: 187
opentargets: metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]
sequence:
MVMHSEDEPYKCKFCGKAFDNLHLYLTHERTHTGEKPYECNKCGKAFSCSSSIRKHARIHTGEKPYICKQCGKAFRYSSSIRNHENTHTGEKPCECKQCGKAFSYSSYFRIHERIHTGEQVYKCKECGKTFTYPSAFHKHKSTHTSQKLYECKECGKAFDCFSSFHSHEGVHTGEKPYECRTWKSLQ


uniprotID: Q86YA3
geneSymbol: ZGRF1
name: Protein ZGRF1 (GRF-type zinc finger domain-containing protein 1)
length: 2104
go: ENSG00000138658;
opentargets: integral component of membrane [GO:0016021]; zinc ion binding [GO:0008270]
snps: rs7696816 rs17854334 rs17669218 rs3828539 rs17605622 rs3762891
location: SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=7;  Name=1; IsoId=Q86YA3-1; Sequence=Displayed; Name=2; IsoId=Q86YA3-2; Sequence=VSP_053232; Name=3; IsoId=Q86YA3-3; Sequence=VSP_053235, VSP_053239, VSP_053241; Name=4; IsoId=Q86YA3-4; Sequence=VSP_053242, VSP_053243; Name=5; IsoId=Q86YA3-5; Sequence=VSP_053237, VSP_053238; Name=6; IsoId=Q86YA3-6; Sequence=VSP_053234, VSP_053236, VSP_053240; Name=7; IsoId=Q86YA3-7; Sequence=VSP_053233, VSP_053244; 


uniprotID: O75290
geneSymbol: ZNF780A
name: Zinc finger protein 780A
length: 641
go: ENSG00000197782;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=O75290-1; Sequence=Displayed; Name=2; IsoId=O75290-2; Sequence=VSP_037718, VSP_037719, VSP_037720; Note=No experimental confirmation available.; Name=3; IsoId=O75290-3; Sequence=VSP_046465; Note=No experimental confirmation available. Gene prediction based on EST data.; 


uniprotID: Q96JM2
geneSymbol: ZNF462
pdb: 1X6F;
name: Zinc finger protein 462 (Zinc finger PBX1-interacting protein) (ZFPIP)
length: 2506
go: ENSG00000148143;
snps: rs17723637 rs3814541 rs3814538 rs7020769 rs10217192
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:20219459, ECO:0000269|PubMed:21570965}.
sequence:

opentargets:
nucleus [GO:0005634]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; chromatin organization [GO:0006325]; negative regulation of DNA binding [GO:0043392]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; IsoId=Q96JM2-1; Sequence=Displayed; Name=2; IsoId=Q96JM2-2; Sequence=VSP_037407, VSP_037408; Note=No experimental confirmation available. {ECO:0000244|PubMed:25755297, ECO:0000244|PubMed:28112733}; Name=3; IsoId=Q96JM2-3; Sequence=VSP_037409; 


uniprotID: Q9Y3M9
geneSymbol: ZNF337
reactome: R-HSA-212436;
name: Zinc finger protein 337
length: 751
go: ENSG00000130684;
snps: rs926487 rs16987972
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9Y3M9-1; Sequence=Displayed; Name=2; IsoId=Q9Y3M9-2; Sequence=VSP_055949; Note=No experimental confirmation available.; 


uniprotID: Q96MU7
geneSymbol: YTHDC1
pdb: 2YUD;4R3H;4R3I;
name: YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B)
length: 727
go: ENSG00000083896;
snps: rs3813832
sequence:

opentargets:
nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; N6-methyladenosine-containing RNA binding [GO:1990247]; RNA binding [GO:0003723]; dosage compensation by inactivation of X chromosome [GO:0009048]; mRNA export from nucleus [GO:0006406]; mRNA splice site selection [GO:0006376]; posttranscriptional regulation of gene expression [GO:0010608]; regulation of mRNA splicing, via spliceosome [GO:0048024]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q96MU7-1; Sequence=Displayed; Name=2; IsoId=Q96MU7-2; Sequence=VSP_006818; 

location:
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:20167602}. Nucleus speckle {ECO:0000269|PubMed:26876937}. Note=Localizes to a novel subnuclear structure, the YT bodies. {ECO:0000250|UniProtKB:Q9QY02}.


uniprotID: Q9UM01
geneSymbol: SLC7A7
reactome: R-HSA-210991;R-HSA-352230;R-HSA-5660862;
length: 511
go: ENSG00000155465;
drug: DB08838;
name:
Y+L amino acid transporter 1 (Monocyte amino acid permease 2) (MOP-2) (Solute carrier family 7 member 7) (y(+)L-type amino acid transporter 1) (Y+LAT1) (y+LAT-1)

sequence:

opentargets:
basolateral plasma membrane [GO:0016323]; integral component of plasma membrane [GO:0005887]; plasma membrane [GO:0005886]; basic amino acid transmembrane transporter activity [GO:0015174]; L-amino acid transmembrane transporter activity [GO:0015179]; cellular amino acid metabolic process [GO:0006520]; leukocyte migration [GO:0050900]; protein-containing complex assembly [GO:0065003]; regulation of arginine metabolic process [GO:0000821]

snps:
rs386833792 rs386833811 rs386833793 rs121908677 rs11568438 rs386833814 rs386833815 rs386833816 rs11568437 rs386833819 rs386833820 rs386833823 rs386833824 rs386833825 rs386833829 rs72552272 rs386833795 rs386833797 rs386833799 rs386833810 

location:
SUBCELLULAR LOCATION: Basolateral cell membrane {ECO:0000269|PubMed:15756301}; Multi-pass membrane protein {ECO:0000269|PubMed:15756301}.


uniprotID: Q96NS1
geneSymbol: YPEL4
name: Protein yippee-like 4
length: 127
go: ENSG00000166793;
opentargets: nucleolus [GO:0005730]; metal ion binding [GO:0046872]
location: SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:15556292}.
sequence:
MPSCDPGPGPACLPTKTFRSYLPRCHRTYSCVHCRAHLAKHDELISKSFQGSHGRAYLFNSVVNVGCGPAEQRLLLTGLHSVADIFCESCKTTLGWKYEQAFETSQKYKEGKYIIEMSHMVKDNGWD


uniprotID: Q6ZPA2
name: Putative uncharacterized protein FLJ26174
length: 131
sequence:
MVPLFITSDSALTYSPLPEPPPTPALGGQRGPPTCQCPDFPYPVPPSEGCPSGRLLLSLHWDWGRGAGGSWSGGAWPGSPGWRLARGPAHGASAESLGPLGKALVTGWEGGWRGGQGGACSPWYFPIPAAL


uniprotID: Q6ZR54
name: Putative uncharacterized protein FLJ46641
length: 194
sequence:
MGKLRPSRGRGFADVSQQIRVRNRPSWACRRGGPLGTLLANAGPSTVPVTPTAGSCQPSPLSPGGSDPPPPPRAHVSPQEAPLGQVPGAEWLPPTRGLLCKDVSSSPGPSFHLGGPGLPGHAGPCGPRARPAQGLAGRGGNVGEGSESPLGTLPCSVPASQQLLRGRSHLQGSLAALGEARGGGAAFSWGQEGP


uniprotID: A8MU76
name: Putative UPF0607 protein ENSP00000381418
length: 341
go: ENSG00000278499;
sequence:


uniprotID: Q8NF99
geneSymbol: ZNF397
length: 534
go: ENSG00000186812;
location: SUBCELLULAR LOCATION: Isoform 1: Nucleus.; SUBCELLULAR LOCATION: Isoform 3: Nucleus. Cytoplasm.
name:
Zinc finger protein 397 (Zinc finger and SCAN domain-containing protein 15) (Zinc finger protein 47)

sequence:

opentargets:
cytoplasm [GO:0005737]; cytosol [GO:0005829]; microtubule cytoskeleton [GO:0015630]; nucleolus [GO:0005730]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; DNA binding [GO:0003677]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; protein heterodimerization activity [GO:0046982]; protein homodimerization activity [GO:0042803]; negative regulation of transcription, DNA-templated [GO:0045892]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=3;  Name=1; Synonyms=ZNF397-fu; IsoId=Q8NF99-1; Sequence=Displayed; Name=2; IsoId=Q8NF99-2; Sequence=VSP_006924, VSP_006925; Note=No experimental confirmation available.; Name=3; Synonyms=Truncated, ZNF397-nf; IsoId=Q8NF99-3; Sequence=VSP_042491, VSP_042492; 


uniprotID: Q6ZRN7
name: Putative uncharacterized protein FLJ46214
length: 208
snps: rs7206805
sequence:


uniprotID: Q96JP5
geneSymbol: ZFP91
pdb: 2M9A;
length: 570
go: ENSG00000186660;
snps: rs17854702 rs8373
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:12738986}.
name:
E3 ubiquitin-protein ligase ZFP91 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ZFP91) (Zinc finger protein 757) (Zinc finger protein 91 homolog) (Zfp-91)

sequence:

opentargets:
nucleolus [GO:0005730]; nucleus [GO:0005634]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; nucleic acid binding [GO:0003676]; ubiquitin-protein transferase activity [GO:0004842]; activation of NF-kappaB-inducing kinase activity [GO:0007250]; protein K63-linked ubiquitination [GO:0070534]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q96JP5-1; Sequence=Displayed; Name=2; IsoId=Q96JP5-2; Sequence=VSP_012686, VSP_012687; 


uniprotID: A8MWP6
name: Uncharacterized protein ENSP00000382042
length: 167
sequence:
MLCPCIQESTFETCLFMAVSQMSKWRLSRVGGSRSLPAEMEVLGEVWCVRAEEQPMTGLGIVWHSPLLDKALETWSLQQQPDFSLGLGHLGLGTDATWMQSFPGSGGDAQAGTGVSGLLRLYPNLLCDFGPRQGPLWALLLEKRQMAGTGGSPALLAWRSASWRALG

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=A8MWP6-1; Sequence=Displayed; Name=2; IsoId=A8MWP6-2; Sequence=VSP_033357; 


uniprotID: A6NDX4
name: Putative transmembrane protein ENSP00000320207
length: 124
opentargets: integral component of membrane [GO:0016021]
location: SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
sequence:
MYVSISFLLGLSHLVLCCLLTFIVNFYLPPESIDFEFMAHNWSKGRSPSSTLGLSWFKAGFRFSDGWSMFYSSGLPGVALPGSPPRSHLLPGTQILIRSFQPCESAKHSARLSSLLTTTSYSVS


uniprotID: Q9C0B9
geneSymbol: ZCCHC2
name: Zinc finger CCHC domain-containing protein 2
length: 1178
go: ENSG00000141664;
snps: rs35643152
sequence:

opentargets:
cytoplasm [GO:0005737]; nucleic acid binding [GO:0003676]; phosphatidylinositol binding [GO:0035091]; zinc ion binding [GO:0008270]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q9C0B9-1; Sequence=Displayed; Name=2; IsoId=Q9C0B9-2; Sequence=VSP_055995; Note=No experimental confirmation available.; 


uniprotID: Q6P2D0
geneSymbol: ZFP1
reactome: R-HSA-212436;
name: Zinc finger protein 1 homolog (Zfp-1) (Zinc finger protein 475)
length: 407
go: ENSG00000184517;
location: SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
sequence:

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q6P2D0-1; Sequence=Displayed; Name=2; IsoId=Q6P2D0-2; Sequence=VSP_012682; Note=No experimental confirmation available.; 


uniprotID: Q8N6K4
name: Putative uncharacterized protein MGC34800
length: 173
sequence:
MGDLPWAPPEAQAPSTAGAGDVAEHQVAPARFLQGAWRQAAGWLCRETGAAPGSAQAGPPETAHAADPQPRGPQAPPRLPPSLSPERVHPGQPAAPAEPAPGAPALRSGPSQPRGLRLPVPVPACAGSSAPGSPAALPDSYPWPPPARNRPATLPPTSRVSPLAAFLASAPQR


uniprotID: P61236
geneSymbol: YPEL3
name: Protein yippee-like 3
length: 119
go: ENSG00000090238;
location: SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:15556292}.
sequence:
MVRISKPKTFQAYLDDCHRRYSCAHCRAHLANHDDLISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIHCENCKTTLGWKYEQAFESSQKYKEGKYIIELNHMIKDNGWD

opentargets:
nucleolus [GO:0005730]; metal ion binding [GO:0046872]; positive regulation of cellular senescence [GO:2000774]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=P61236-1; Sequence=Displayed; Name=2; IsoId=P61236-2; Sequence=VSP_037276; 


uniprotID: Q6ZSA8
name: Putative uncharacterized protein FLJ45684
length: 131
sequence:
METANGEEPPAGPPVSLHGRRLLRVGGACPTPLPVLQRLPPSALHHTLHCVPRRVCVSPLGQVTRIPPVRTVRRAPSGLLPQRRGGPSWWPPSGVARGGPSWWPPSGVVRGGPSSWPPSGVAEPREALGLP


uniprotID: Q8N5P1
geneSymbol: ZC3H8
reactome: R-HSA-6807505;
name: Zinc finger CCCH domain-containing protein 8
length: 291
go: ENSG00000144161;
snps: rs35782954
sequence:

opentargets:
Cajal body [GO:0015030]; histone locus body [GO:0035363]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; transcription elongation factor complex [GO:0008023]; transcriptionally active chromatin [GO:0035327]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001227]; metal ion binding [GO:0046872]; RNA binding [GO:0003723]; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding [GO:0001162]; sequence-specific DNA binding [GO:0043565]; apoptotic process [GO:0006915]; negative regulation of T cell differentiation in thymus [GO:0033085]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of thymocyte apoptotic process [GO:0070245]; positive regulation of transcription by RNA polymerase III [GO:0045945]; response to antibiotic [GO:0046677]; snRNA transcription by RNA polymerase II [GO:0042795]; snRNA transcription by RNA polymerase III [GO:0042796]; T cell homeostasis [GO:0043029]

location:
SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:23932780}. Note=Colocalizes with coilin in subnuclear cajal and histone locus bodies. Translocates in the LEC complex to cajal and histone locus bodies at snRNA genes in a ICE1-dependent manner. Associates to transcriptionally active chromatin at snRNA genes.


uniprotID: P61129
geneSymbol: ZC3H6
name: Zinc finger CCCH domain-containing protein 6
length: 1189
go: ENSG00000188177;
sequence:

opentargets:
nucleus [GO:0005634]; DNA-binding transcription factor activity [GO:0003700]; DNA-binding transcription factor activity, RNA polymerase II-specific [GO:0000981]; metal ion binding [GO:0046872]; RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding [GO:0001162]; negative regulation of transcription, DNA-templated [GO:0045892]


uniprotID: Q8N8P6
name: Putative uncharacterized protein FLJ39060
length: 123
sequence:
MVDGRTRTIINDIFFTEPTPEMSSLPVRSHSSLSLNLVSLMVICRGIIKLVIHFRMYCPPRLKAKHIEPTLRPVPLKELRISHWPNECIRHSASVPMATGANGLETKDETKRNAEKCACSVFL


uniprotID: P63098
geneSymbol: PPP3R1
reactome: R-HSA-111447;R-HSA-180024;R-HSA-2025928;R-HSA-2871809;R-HSA-4086398;R-HSA-5607763;
pdb: 1AUI;1M63;1MF8;2P6B;3LL8;4F0Z;4OR9;4ORA;4ORC;5SVE;
length: 170
go: ENSG00000221823;
drug: DB04906;DB08231;
name:
Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1)

sequence:
MGNEASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKMVVDV

opentargets:
calcineurin complex [GO:0005955]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; sarcolemma [GO:0042383]; calcium ion binding [GO:0005509]; calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calmodulin binding [GO:0005516]; cyclosporin A binding [GO:0016018]; phosphatase binding [GO:0019902]; protein domain specific binding [GO:0019904]; calcineurin-NFAT signaling cascade [GO:0033173]; Fc-epsilon receptor signaling pathway [GO:0038095]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Wnt signaling pathway, calcium modulating pathway [GO:0007223]

location:
SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q63810}. Cell membrane {ECO:0000250|UniProtKB:Q63810}. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:Q63810}. Cell membrane {ECO:0000269|PubMed:25255805}; Lipid-anchor {ECO:0000269|PubMed:25255805}. Note=Translocates from the cytosol to the sarcolemma in a CIB1-dependent manner during cardiomyocyte hypertrophy. {ECO:0000250|UniProtKB:Q63810}.


uniprotID: Q92793
geneSymbol: CREBBP
name: CREB-binding protein (EC 2.3.1.48)
length: 2442
go: ENSG00000005339;
reactome:
R-HSA-1234158;R-HSA-1368082;R-HSA-1368108;R-HSA-1912408;R-HSA-1989781;R-HSA-201722;R-HSA-210744;R-HSA-2122947;R-HSA-2151201;R-HSA-2426168;R-HSA-2644606;R-HSA-2894862;R-HSA-3134973;R-HSA-3214847;R-HSA-3371568;R-HSA-350054;R-HSA-381340;R-HSA-3899300;R-HSA-400206;R-HSA-400253;R-HSA-5617472;R-HSA-5621575;R-HSA-6803204;R-HSA-8866907;R-HSA-8939246;R-HSA-8941856;R-HSA-9013508;R-HSA-9013695;R-HSA-9018519;R-HSA-918233;R-HSA-933541;

pdb:
1JSP;1LIQ;1RDT;1WO3;1WO4;1WO5;1WO6;1WO7;1ZOQ;2D82;2KJE;2KWF;2L84;2L85;2LXS;2LXT;2N1A;2RNY;3DWY;3P1C;3P1D;3P1E;3P1F;3SVH;4A9K;4N3W;4N4F;4NR4;4NR5;4NR6;4NR7;4NYV;4NYW;4NYX;4OUF;4TQN;4TS8;4WHU;4YK0;5CGP;5DBM;5EIC;5ENG;5EP7;5GH9;5H85;5I83;5I86;5I89;5I8B;5I8G;5J0D;5JEM;5KTU;5KTW;5KTX;5LPJ;5LPL;5MME;5MMG;5MPK;5MPN;5MPZ;5MQE;5MQG;5MQK;5NLK;5NRW;5NU3;5OWK;5SVH;5TB6;5W0E;5W0F;5W0L;5W0Q;5XXH;6ALC;6AXQ;6AY3;6AY5;6FQO;6FQU;6FR0;6FRF;

sequence:

opentargets:
cytoplasm [GO:0005737]; histone acetyltransferase complex [GO:0000123]; nuclear body [GO:0016604]; nuclear chromatin [GO:0000790]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; acetyltransferase activity [GO:0016407]; chromatin binding [GO:0003682]; damaged DNA binding [GO:0003684]; DNA-binding transcription factor activity [GO:0003700]; histone acetyltransferase activity [GO:0004402]; MRF binding [GO:0043426]; p53 binding [GO:0002039]; peptide N-acetyltransferase activity [GO:0034212]; proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific [GO:0001078]; proximal promoter sequence-specific DNA binding [GO:0000987]; RNA polymerase II activating transcription factor binding [GO:0001102]; RNA polymerase II transcription factor binding [GO:0001085]; transcription coactivator activity [GO:0003713]; transcription factor binding [GO:0008134]; zinc ion binding [GO:0008270]; beta-catenin-TCF complex assembly [GO:1904837]; cellular response to UV [GO:0034644]; embryonic digit morphogenesis [GO:0042733]; histone acetylation [GO:0016573]; homeostatic process [GO:0042592]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription of Notch receptor target [GO:0007221]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of type I interferon production [GO:0032481]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to heat [GO:1900034]; regulation of lipid metabolic process [GO:0019216]; regulation of myeloid cell differentiation [GO:0045637]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; regulation of transcription, DNA-templated [GO:0006355]; response to hypoxia [GO:0001666]; rhythmic process [GO:0048511]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; transcription initiation from RNA polymerase II promoter [GO:0006367]; viral process [GO:0016032]

snps:
rs748447855 rs902901184 rs746728741 rs143247685 rs28937315 rs267606752 rs121434626 rs130015 rs797044860 rs1057520191 rs1131691326 rs886039491 rs797045037 

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=2;  Name=1; IsoId=Q92793-1; Sequence=Displayed; Name=2; IsoId=Q92793-2; Sequence=VSP_045700; Note=No experimental confirmation available.; 

location:
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Recruited to nuclear bodies by SS18L1/CREST. In the presence of ALX1 relocalizes from the cytoplasm to the nucleus.


uniprotID: P16070
geneSymbol: CD44
reactome: R-HSA-1474228;R-HSA-202733;R-HSA-216083;R-HSA-2160916;R-HSA-6798695;R-HSA-877300;
pdb: 1POZ;1UUH;2I83;4PZ3;4PZ4;
length: 742
go: ENSG00000026508;
drug: DB08818;
snps: rs369473842 rs11607491 rs9666607 rs1467558 rs12273397
name:
CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)

sequence:

opentargets:
apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cell projection [GO:0042995]; cell surface [GO:0009986]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; lamellipodium membrane [GO:0031258]; macrophage migration inhibitory factor receptor complex [GO:0035692]; microvillus [GO:0005902]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; collagen binding [GO:0005518]; hyaluronic acid binding [GO:0005540]; transmembrane signaling receptor activity [GO:0004888]; cartilage development [GO:0051216]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; cellular response to fibroblast growth factor stimulus [GO:0044344]; extracellular matrix disassembly [GO:0022617]; extracellular matrix organization [GO:0030198]; hyaluronan catabolic process [GO:0030214]; inflammatory response [GO:0006954]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte migration [GO:0050900]; monocyte aggregation [GO:0070487]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; neutrophil degranulation [GO:0043312]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of monocyte aggregation [GO:1900625]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of lamellipodium morphogenesis [GO:2000392]; wound healing, spreading of cells [GO:0044319]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=19;  Comment=Additional isoforms seem to exist. Additional isoforms are produced by alternative splicing of 10 out of 19 exons within the extracellular domain. Additional diversity is generated through the utilization of internal splice donor and acceptor sites within 2 of the exons. A variation in the cytoplasmic domain was shown to result from the alternative splicing of 2 exons. Isoform CD44 is expected to be expressed in normal cells. Splice variants have been found in many tumor cell lines. Exons 5, 6, 7, 8, 9, 10, 11, 13, 14 and 19 are alternatively spliced. Experimental confirmation may be lacking for some isoforms. {ECO:0000269|PubMed:1465456}; Name=1; Synonyms=CD44; IsoId=P16070-1; Sequence=Displayed; Note=Corresponds to the largest isoform.; Name=2; Synonyms=CD44SP; IsoId=P16070-2; Sequence=VSP_005303, VSP_005304; Name=3; IsoId=P16070-3; Sequence=VSP_005305, VSP_005306; Note=Alternative splice donor/acceptor on exon 5.; Name=4; Synonyms=Epidermal; IsoId=P16070-4; Sequence=VSP_005307, VSP_005308; Note=Lacks exon 6.; Name=5; IsoId=P16070-5; Sequence=VSP_005313; Note=Alternative splice donor/acceptor on exon 7.; Name=6; IsoId=P16070-6; Sequence=VSP_005314, VSP_005315; Note=Lacks exon 10.; Name=7; IsoId=P16070-7; Sequence=VSP_005316, VSP_005317; Note=Lacks exon 13.; Name=8; IsoId=P16070-8; Sequence=VSP_005318, VSP_005319; Note=Lacks exon 14.; Name=9; IsoId=P16070-9; Sequence=VSP_005320, VSP_005321; Note=Lacks exon 19.; Name=10; Synonyms=CD44E, CD44R1, Epithelial, Keratinocyte; IsoId=P16070-10; Sequence=VSP_005309, VSP_005310; Note=Lacks exons 6-11.; Name=11; Synonyms=CD44R2; IsoId=P16070-11; Sequence=VSP_022797; Note=Lacks exons 6-13.; Name=12; Synonyms=CDw44, Reticulocyte; IsoId=P16070-12; Sequence=VSP_005311, VSP_005312; Note=Lacks exons 6-14.; Name=13; Synonyms=CD44R4; IsoId=P16070-13; Sequence=VSP_005309, VSP_005310, VSP_005318, VSP_005319; Note=Lacks exons 6-11 and exon 14.; Name=14; Synonyms=CD44R5; IsoId=P16070-14; Sequence=VSP_005309, VSP_005310, VSP_005316, VSP_005317, VSP_005318, VSP_005319; Note=Lacks exons 6-11, exon 13 and exon 14.; Name=15; Synonyms=Hermes; IsoId=P16070-15; Sequence=VSP_005311, VSP_005312, VSP_005320, VSP_005321; Note=Lacks exons 6-14 and exon 19.; Name=16; IsoId=P16070-16; Sequence=VSP_005305, VSP_005306, VSP_005314, VSP_005315; Note=Alternative splice donor/acceptor on exon 5 and lacks exon 10.; Name=17; IsoId=P16070-17; Sequence=VSP_005313, VSP_005314, VSP_005315; Note=Alternative splice donor/acceptor on exon 7 and lacks exon 10.; Name=18; IsoId=P16070-18; Sequence=VSP_005311, VSP_005312, VSP_043575; Note=No experimental confirmation available.; Name=19; Synonyms=CD44RC; IsoId=P16070-19; Sequence=VSP_043870, VSP_043871; Note=Soluble isoform, has enhanced hyaluronan binding.; 

location:
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P15379}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P15379}. Cell projection, microvillus {ECO:0000250|UniProtKB:P15379}. Note=Colocalizes with actin in membrane protrusions at wounding edges. Co-localizes with RDX, EZR and MSN in microvilli. {ECO:0000250|UniProtKB:P15379}.


uniprotID: A6NJW9
geneSymbol: CD8B2
name: Putative T-cell surface glycoprotein CD8 beta-2 chain (CD8b pseudogene)
length: 211
sequence:

opentargets:
integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; adaptive immune response [GO:0002250]


uniprotID: P15812
geneSymbol: CD1E
pdb: 3S6C;
length: 388
go: ENSG00000158488;
snps: rs3180089 rs2873587 rs1065457 rs35116276 rs199655202 rs200741122
name:
T-cell surface glycoprotein CD1e, membrane-associated (hCD1e) (R2G1) (CD antigen CD1e) [Cleaved into: T-cell surface glycoprotein CD1e, soluble (sCD1e)]

sequence:

opentargets:
cell surface [GO:0009986]; early endosome [GO:0005769]; Golgi membrane [GO:0000139]; integral component of plasma membrane [GO:0005887]; late endosome [GO:0005770]; lysosomal lumen [GO:0043202]; plasma membrane [GO:0005886]; endogenous lipid antigen binding [GO:0030883]; exogenous lipid antigen binding [GO:0030884]; lipopeptide binding [GO:0071723]; adaptive immune response [GO:0002250]; antigen processing and presentation, endogenous lipid antigen via MHC class Ib [GO:0048006]; antigen processing and presentation, exogenous lipid antigen via MHC class Ib [GO:0048007]; immune response [GO:0006955]; positive regulation of T cell mediated cytotoxicity [GO:0001916]

isoforms:
ALTERNATIVE PRODUCTS:  Event=Alternative splicing; Named isoforms=13;  Name=1; IsoId=P15812-1; Sequence=Displayed; Name=2; IsoId=P15812-2; Sequence=VSP_037713; Name=3; IsoId=P15812-3; Sequence=VSP_037711, VSP_037712; Name=4; IsoId=P15812-4; Sequence=VSP_037710, VSP_037713; Name=5; IsoId=P15812-5; Sequence=VSP_037709; Name=6; IsoId=P15812-6; Sequence=VSP_037709, VSP_037713; Name=7; IsoId=P15812-7; Sequence=VSP_037709, VSP_037710, VSP_037713; Name=8; IsoId=P15812-8; Sequence=VSP_037708; Name=9; IsoId=P15812-9; Sequence=VSP_037708, VSP_037713; Name=10; IsoId=P15812-10; Sequence=VSP_037708, VSP_037711, VSP_037712; Name=11; IsoId=P15812-11; Sequence=VSP_037708, VSP_037710; Name=12; IsoId=P15812-12; Sequence=VSP_037708, VSP_037710, VSP_037713; Name=13; IsoId=P15812-13; Sequence=VSP_046961; 

location:
SUBCELLULAR LOCATION: T-cell surface glycoprotein CD1e, membrane-associated: Golgi apparatus membrane; Single-pass type I membrane protein. Early endosome. Late endosome. Note=Predominantly localized in the trans-Golgi network in immature dendritic cells, and as a cleaved, soluble protein in the lysosome lumen of mature dendritic cells.; SUBCELLULAR LOCATION: T-cell surface glycoprotein CD1e, soluble: Lysosome lumen.


